⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9737536 | 1.00 | — | — | |
| SCHEMBL3831331 | 0.81 | — | — | |
| SCHEMBL13938736 | 0.78 | GPR119 (0.34) | — | |
| SCHEMBL3245496 | 0.78 | GPR119 (0.34) | — | |
| SCHEMBL12429271 | 0.75 | PPM1D (0.31) | — | |
| SCHEMBL12429274 | 0.73 | PPM1D (0.30) | — | |
| SCHEMBL9738384 | 0.72 | TOP2A (0.33) | — | |
| SCHEMBL13866330 | 0.72 | — | — | |
| SCHEMBL21072420 | 0.72 | — | — | |
| SCHEMBL14010182 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0251164-B1 | NEW CHIRAL PHOSPHINOPYRROLIDINE COMPOUNDS AND THEIR USE FOR ASYMETRIC SYNTHESIS OF OPTICALLY ACTIVE COMPOUNDS | Achiwa, Kazuo (JP) | 1992-12-16 | — | — | EP | disclosed |
| US-4879389-A | HYDROGENATION CATALYSTS | ACHIWA KAZUO (JP) | 1989-11-07 | — | — | US | disclosed |
| EP-0251164-A2 | New chiral phosphinopyrrolidine compounds and their use for asymetric synthesis of optically active compounds | Achiwa, Kazuo (JP) | 1988-01-07 | — | — | EP | disclosed |