⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13938736 | 0.87 | GPR119 (0.34) | — | |
| SCHEMBL3245496 | 0.87 | GPR119 (0.34) | — | |
| SCHEMBL21802121 | 0.85 | PPM1D (0.33) | — | |
| SCHEMBL15519418 | 0.85 | — | — | |
| SCHEMBL25364563 | 0.83 | ABHD6 (0.31) | — | |
| SCHEMBL4041770 | 0.82 | ATM (0.34) | — | |
| SCHEMBL4041777 | 0.82 | ATM (0.34) | — | |
| SCHEMBL20973729 | 0.82 | ATM (0.34) | — | |
| SCHEMBL5569321 | 0.82 | ATM (0.34) | — | |
| SCHEMBL18426092 | 0.82 | MMP2 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090312310-A1 | Imidazothiazole derivatives | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2009-12-17 | — | — | US | disclosed |
| EP-2103619-A1 | IMIDAZOTHIAZOLE DERIVATIVES | Daiichi Sankyo Company, Limited (JP) | 2009-09-23 | — | — | EP | disclosed |