Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.46 |
| ▸ | MEN1 | O00255 | 6/20 | 0.46 |
| ▸ | POLB | P06746 | 4/20 | 0.46 |
| ▸ | BLM | P54132 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9766388 | 0.84 | MEN1 (0.58) | L3MBTL1KMT2AMEN1ALDH1A1GAA | |
| SCHEMBL11405716 | 0.68 | QPCT (0.52) | L3MBTL1KMT2AMEN1POLBBLM | |
| SCHEMBL22904470 | 0.67 | KMT2A (0.56) | L3MBTL1KMT2AMEN1POLBBLM | |
| SCHEMBL32688379 | 0.66 | ALDH1A1 (0.80) | L3MBTL1KMT2AMEN1POLBBLM | |
| SCHEMBL9240440 | 0.65 | L3MBTL1 (1.00) | L3MBTL1KMT2AMEN1POLBBLM | |
| SCHEMBL14338607 | 0.64 | ALDH1A1 (0.59) | L3MBTL1KMT2AMEN1POLBBLM | |
| SCHEMBL20053775 | 0.64 | ALDH1A1 (0.66) | L3MBTL1KMT2AMEN1POLBBLM | |
| SCHEMBL14879987 | 0.63 | ALDH1A1 (0.65) | L3MBTL1KMT2AMEN1POLBBLM | |
| SCHEMBL30281285 | 0.63 | KMO (0.54) | KMT2AMEN1ALDH1A1KDM4EGAA | |
| SCHEMBL3653503 | 0.63 | KMO (0.54) | L3MBTL1KMT2AMEN1POLBBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5112938-A | CYANO- AND CARBOXY-SUBSTITUTED SPIRODILACTAMS | SHELL OIL COMPANY (US) | 1992-05-12 | — | — | US | disclosed |
| US-5037948-A | Cyano- and carboxy-substituted spirodilactams | SHELL OIL COMPANY (US) | 1991-08-06 | — | — | US | disclosed |