Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 3/20 | 0.35 |
| ▸ | CTSB | P07858 | 2/20 | 0.35 |
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9194470 | 0.84 | CES2 (0.41) | SMN1; SMN2MEN1KMT2AALDH1A1NPC1 | |
| Cyclopentane SCHEMBL20528160 | 0.78 | MAPT (0.33) | MEN1KMT2AMAPT | |
| Cycloheptane SCHEMBL20528163 | 0.78 | MAPT (0.33) | MEN1KMT2AMAPT | |
| SCHEMBL28549878 | 0.78 | PAX8 (0.39) | SMN1; SMN2MEN1KMT2AALDH1A1MAPT | |
| Cyclohexane SCHEMBL20528150 | 0.78 | MAPT (0.33) | MEN1KMT2AMAPT | |
| SCHEMBL5685765 | 0.76 | GAA (0.40) | MEN1KMT2AALDH1A1GAATDP1 | |
| SCHEMBL9197406 | 0.75 | CYP3A4 (0.38) | SMN1; SMN2MEN1KMT2AALDH1A1NPC1 | |
| SCHEMBL18775796 | 0.74 | NPC1 (0.33) | SMN1; SMN2MEN1KMT2AALDH1A1NPC1 | |
| SCHEMBL27572592 | 0.74 | ALDH1A1 (0.43) | MEN1KMT2AALDH1A1EPHX2POLB | |
| SCHEMBL434421 | 0.74 | MGAM (0.52) | SMN1; SMN2MEN1KMT2AALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5173495-A | 7-[(2,6-dialkyl-4-furyl or thienyl-pyridyl)]-3,5-di-(dihydroxy-6-enoates) useful for treating circulatory diseases | BAYER AKTIENGESELLSCHAFT (DE) | 1992-12-22 | — | — | US | disclosed |
| US-4968689-A | Certain 2,6-diisopropyl-4-(4-fluoro-phenyl)-3,5-bis-dimethyl-3',5'-dihydroxy-hept-6-enoate-pyridine derivatives useful for treating lipoproteinaemia and arteriosclerosis | BAYER AKTIENGESELLSCHAFT (DE) | 1990-11-06 | — | — | US | disclosed |