Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9738208 | 0.91 | GAA (0.34) | APPKMT2AMEN1ALDH1A1POLB | |
| SCHEMBL9737943 | 0.89 | APP (0.38) | APPKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL9738054 | 0.88 | MAPT (0.41) | KMT2AMEN1ALDH1A1LMNAGAA | |
| SCHEMBL9739096 | 0.88 | PDE4A (0.40) | APPKMT2AMEN1ALDH1A1GAA | |
| SCHEMBL9737830 | 0.85 | APP (0.40) | APPKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL7291523 | 0.82 | APP (0.41) | APPKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL7297676 | 0.80 | APP (0.39) | APPKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL7290314 | 0.80 | APP (0.39) | APPKMT2AMEN1ALDH1A1GAA | |
| SCHEMBL10365856 | 0.77 | APP (0.44) | APPKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL10365961 | 0.77 | APP (0.43) | APPKMT2AMEN1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5153194-A | Anxiolytic agents | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1992-10-06 | — | — | US | claimed |
| US-5153194-A | Anxiolytic agents | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1992-10-06 | — | — | US | disclosed |