Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 5/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 5/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 5/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9738208 | 0.92 | GAA (0.34) | PDE4APDE4BPDE4CPDE4DMAPT | |
| SCHEMBL9738054 | 0.89 | MAPT (0.41) | KDM4EMAPTMEN1ALDH1A1GAA | |
| SCHEMBL9738168 | 0.88 | APP (0.41) | PDE4APDE4BPDE4CPDE4DMAPT | |
| SCHEMBL7379907 | 0.80 | PDE4A (0.40) | PDE4APDE4BPDE4CPDE4DKDM4E | |
| SCHEMBL9737592 | 0.77 | MAPT (0.36) | KDM4EMAPTMEN1ALDH1A1TSHR | |
| SCHEMBL9738670 | 0.76 | ACHE (0.41) | MAPTMEN1ALDH1A1GAAKMT2A | |
| SCHEMBL9737943 | 0.76 | APP (0.38) | PDE4APDE4BPDE4CPDE4DKDM4E | |
| SCHEMBL8840956 | 0.76 | GABRP (0.50) | KDM4EMAPTMEN1ALDH1A1KMT2A | |
| SCHEMBL10367572 | 0.75 | KDM4E (0.44) | PDE4APDE4BPDE4CPDE4DKDM4E | |
| SCHEMBL8840985 | 0.74 | ACHE (0.34) | PDE4APDE4BPDE4CPDE4DMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5153194-A | Anxiolytic agents | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1992-10-06 | — | — | US | claimed |
| US-5153194-A | Anxiolytic agents | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1992-10-06 | — | — | US | disclosed |