Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | PTH1R | Q03431 | 1/20 | 0.31 |
| ▸ | EP300 | Q09472 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9738054 | 0.93 | MAPT (0.41) | GAAMAPTNPC1HTTPTH1R | |
| SCHEMBL9739096 | 0.92 | PDE4A (0.40) | GAAMAPTPDE4APDE4BPDE4C | |
| SCHEMBL9738168 | 0.91 | APP (0.41) | GAAMAPTPDE4APDE4BPDE4C | |
| SCHEMBL9738670 | 0.84 | ACHE (0.41) | GAAMAPTSRCHTTMEN1 | |
| SCHEMBL8840985 | 0.81 | ACHE (0.34) | GAAMAPTNPC1PDE4APDE4B | |
| SCHEMBL7379926 | 0.80 | MAPT (0.33) | GAAMAPTNPC1PDE4APDE4B | |
| SCHEMBL9411277 | 0.80 | GABRP (0.38) | GAAMAPTNPC1HTTEP300 | |
| SCHEMBL9737592 | 0.80 | MAPT (0.36) | MAPTNPC1PTGS2HTTPTH1R | |
| SCHEMBL9737943 | 0.79 | APP (0.38) | GAAMAPTPDE4APDE4BPDE4C | |
| SCHEMBL8840975 | 0.79 | NPC1 (0.32) | GAAMAPTNPC1PDE4APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5153194-A | Anxiolytic agents | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1992-10-06 | — | — | US | claimed |
| US-5153194-A | Anxiolytic agents | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1992-10-06 | — | — | US | disclosed |