Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9738670 | 0.89 | ACHE (0.41) | BCHEACHEKMT2AGAAMEN1 | |
| SCHEMBL8840949 | 0.86 | ACHE (0.43) | BCHEACHEKMT2AMEN1ALDH1A1 | |
| SCHEMBL9738168 | 0.85 | APP (0.41) | APPKMT2AGAAMEN1CA12 | |
| SCHEMBL9737943 | 0.84 | APP (0.38) | APPKMT2AGAAMEN1CA12 | |
| SCHEMBL7286897 | 0.82 | POLB (0.43) | APPKMT2AGAAMEN1CA12 | |
| SCHEMBL8840999 | 0.82 | ACHE (0.47) | BCHEACHEGAAPOLBALDH1A1 | |
| SCHEMBL8840973 | 0.79 | ACHE (0.48) | BCHEACHEKMT2AMEN1ALDH1A1 | |
| SCHEMBL10365961 | 0.77 | APP (0.43) | APPACHEKMT2AGAAMEN1 | |
| SCHEMBL10365856 | 0.75 | APP (0.44) | APPKMT2AGAAMEN1CA12 | |
| SCHEMBL7290542 | 0.74 | MAPT (0.41) | APPACHEKMT2AGAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5153194-A | Anxiolytic agents | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1992-10-06 | — | — | US | claimed |
| US-5153194-A | Anxiolytic agents | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1992-10-06 | — | — | US | disclosed |