Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.44 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.43 |
| ▸ | VNN1 | O95497 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | AURKA | O14965 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2032760 | 0.87 | L3MBTL1 (0.54) | MEN1KMT2AL3MBTL1CYP1A2CYP2C9 | |
| SCHEMBL12515566 | 0.83 | MEN1 (0.47) | MEN1KMT2AL3MBTL1CYP1A2CYP2C9 | |
| SCHEMBL6209176 | 0.83 | MEN1 (0.47) | MEN1KMT2AL3MBTL1CYP1A2CYP2C9 | |
| SCHEMBL22261128 | 0.81 | JAK3 (0.57) | VNN1AURKARPS6KB1 | |
| SCHEMBL12069119 | 0.80 | APP (0.55) | ATMEGFR | |
| SCHEMBL25436218 | 0.79 | VNN1 (0.50) | MEN1KMT2AL3MBTL1CYP1A2CYP2C9 | |
| SCHEMBL3844908 | 0.76 | PRKCQ (0.42) | MEN1KMT2AHPGDADORA3ADORA1 | |
| SCHEMBL11013921 | 0.73 | KDM4C (0.54) | MEN1KMT2AL3MBTL1CYP1A2CYP2C9 | |
| SCHEMBL9476148 | 0.73 | MEN1 (0.48) | MEN1KMT2AL3MBTL1CYP1A2CYP2C9 | |
| SCHEMBL7257523 | 0.73 | ALDH1A1 (0.48) | L3MBTL1CYP1A2CYP2C19ALDH1A1MAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5110818-A | Antiepileptic agents | CIBA-GEIGY CORPORATION (US) | 1992-05-05 | — | — | US | disclosed |
| EP-0363320-A2 | Substituted 9H purine | CIBA-GEIGY AG (CH) | 1990-04-11 | — | — | EP | disclosed |