Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9738378 | 0.78 | PKM (0.36) | KMT2APKMKDM4EPOLBCTDSP1 | |
| SCHEMBL8696566 | 0.76 | PKM (0.56) | KMT2APKMSMN1; SMN2KDM4EPOLB | |
| SCHEMBL8697678 | 0.74 | KMT2A (0.35) | KMT2APKMSMN1; SMN2KDM4EPOLB | |
| SCHEMBL10591013 | 0.72 | PKM (0.34) | PKMKDM4EPOLBCTDSP1TDP1 | |
| SCHEMBL8695352 | 0.67 | PKM (0.36) | KMT2APKMKDM4EPOLBCTDSP1 | |
| SCHEMBL9738984 | 0.63 | KMT2A (0.33) | KMT2AKDM4EALDH1A1MEN1 | |
| SCHEMBL621983 | 0.63 | PKM (0.69) | KMT2APKMSMN1; SMN2KDM4EPOLB | |
| SCHEMBL30105934 | 0.63 | PKM (0.69) | KMT2APKMSMN1; SMN2KDM4EPOLB | |
| SCHEMBL28114768 | 0.62 | ALDH1A1 (0.53) | KMT2APKMSMN1; SMN2KDM4EPOLB | |
| SCHEMBL28506852 | 0.62 | PKM (0.48) | KMT2APKMSMN1; SMN2KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5089046-A | Herbicides or miticide | SANDOZ LTD. (CH) | 1992-02-18 | — | — | US | disclosed |
| EP-0336898-A2 | Substituted aryl or heteroaryl diones | SANDOZ AG (CH) | 1989-10-11 | — | — | EP | disclosed |