Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8695352 | 0.80 | PKM (0.36) | KMT2APKMHTTALDH1A1LMNA | |
| SCHEMBL8696566 | 0.75 | PKM (0.56) | KMT2ASMN1; SMN2PKMALDH1A1MEN1 | |
| SCHEMBL4653029 | 0.75 | ALDH1A1 (0.37) | KMT2AHTTALDH1A1MEN1NPC1 | |
| SCHEMBL9738558 | 0.74 | KMT2A (0.34) | KMT2ASMN1; SMN2PKMALDH1A1MEN1 | |
| SCHEMBL8698297 | 0.72 | TXNRD1 (0.43) | KMT2AALDH1A1MEN1NPC1MAPT | |
| SCHEMBL8699992 | 0.71 | MAPT (0.33) | KMT2ASMN1; SMN2ALDH1A1MEN1NPC1 | |
| SCHEMBL8698410 | 0.69 | HPGD (0.43) | KMT2ASMN1; SMN2PKMALDH1A1MEN1 | |
| SCHEMBL9738378 | 0.69 | PKM (0.36) | KMT2APKMALDH1A1MEN1LMNA | |
| SCHEMBL6099839 | 0.68 | THRB (0.32) | — | |
| SCHEMBL14040678 | 0.67 | TSHR (0.52) | KMT2ASMN1; SMN2PKMHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5801120-A | HERBICIDES FOR CONTROLLING WEEDS | SANDOZ LTD. (CH) | 1998-09-01 | — | — | US | disclosed |
| US-5700762-A | HERBICIDES | SANDOZ LTD. (CH) | 1997-12-23 | — | — | US | disclosed |
| US-5608101-A | HERBICIDES | NOVARTIS AG (CH) | 1997-03-04 | — | — | US | disclosed |
| EP-0338992-A2 | Substituted aryl and heteroaryl bicyclodiones | SANDOZ AG (CH) | 1989-10-25 | — | — | EP | disclosed |