Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.38 |
| ▸ | HPGD | P15428 | 8/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.38 |
| ▸ | GLA | P06280 | 5/20 | 0.38 |
| ▸ | GAA | P10253 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 5/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | CASP1 | P29466 | 2/20 | 0.34 |
| ▸ | CASP7 | P55210 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.34 |
| ▸ | YWHAG | P61981 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | KDM1A | O60341 | 2/20 | 0.33 |
| ▸ | CUL4A | Q13619 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10703931 | 0.81 | MAPT (0.42) | ALDH1A1KMT2AKDM4EGAAMEN1 | |
| SCHEMBL8178191 | 0.79 | MAOB (0.55) | GAAMAPTL3MBTL1CYP2C19LMNA | |
| SCHEMBL6499286 | 0.77 | DRD3 (0.43) | CASP1TSHRKDM1A | |
| SCHEMBL8173176 | 0.75 | MAOB (0.47) | KDM1A | |
| SCHEMBL9059555 | 0.69 | CHRNB2 (0.36) | ALDH1A1HPGDKMT2AMEN1 | |
| SCHEMBL13318482 | 0.67 | TSHR (0.39) | ALDH1A1KMT2AKDM4EMEN1MAPT | |
| SCHEMBL3972334 | 0.67 | KDM1A (0.43) | ALDH1A1KMT2AMEN1L3MBTL1TSHR | |
| SCHEMBL17660056 | 0.67 | KDM1A (0.43) | ALDH1A1KMT2AMEN1L3MBTL1TSHR | |
| SCHEMBL5955814 | 0.67 | KDM1A (0.43) | ALDH1A1KMT2AMEN1L3MBTL1TSHR | |
| SCHEMBL18298261 | 0.67 | TSHR (0.39) | ALDH1A1KMT2AKDM4EMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116239573-B | Preparation method and application of metal organic quaternary cyclic compound | 大连理工大学 | 2024-03-26 | — | — | CN | disclosed |
| CN-116239573-A | Preparation method and application of metal organic quaternary cyclic compound | 大连理工大学 | 2023-06-09 | — | — | CN | disclosed |
| US-5082842-A | Sedatives | HOFFMANN-LA ROCHE INC. (US) | 1992-01-21 | — | — | US | disclosed |
| US-4889854-A | MUSCLE RELAXANT, SEDATIVE-HYPNOTIC, ANXIOLYTIC AND-OR ANTICONVULSANT ACTIVITY | HOFFMAN-LA ROCHE INC. (US) | 1989-12-26 | — | — | US | disclosed |
| EP-0294599-A2 | Tricyclic pyridone derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1988-12-14 | — | — | EP | disclosed |