Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | TERT | O14746 | 1/20 | 0.42 |
| ▸ | S100B | P04271 | 1/20 | 0.41 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.40 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 6/20 | 0.38 |
| ▸ | MEN1 | O00255 | 5/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | ACHE | P22303 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7479982 | 0.92 | ALDH1A1 (0.40) | ALDH1A1L3MBTL1MAPK1CYP3A4TDP1 | |
| SCHEMBL10893246 | 0.85 | MAPK1 (0.40) | ALDH1A1L3MBTL1MAPK1TDP1TSHR | |
| SCHEMBL9480308 | 0.83 | CNR2 (0.35) | ALDH1A1L3MBTL1MAPK1CYP3A4TSHR | |
| SCHEMBL9509481 | 0.82 | ALDH1A1 (0.40) | ALDH1A1L3MBTL1MAPK1CYP3A4TDP1 | |
| SCHEMBL8064164 | 0.76 | ALDH1A1 (0.44) | ALDH1A1L3MBTL1MAPK1CYP3A4TDP1 | |
| SCHEMBL1637760 | 0.75 | S100B (0.47) | ALDH1A1L3MBTL1MAPK1CYP3A4TDP1 | |
| SCHEMBL7153357 | 0.73 | ALDH1A1 (0.64) | ALDH1A1L3MBTL1MAPK1CYP3A4TDP1 | |
| SCHEMBL11547210 | 0.73 | ALDH1A1 (0.64) | ALDH1A1L3MBTL1MAPK1CYP3A4TDP1 | |
| SCHEMBL16167543 | 0.73 | ALDH1A1 (0.42) | ALDH1A1L3MBTL1MAPK1CYP3A4TDP1 | |
| SCHEMBL9320695 | 0.72 | ALDH1A1 (0.56) | ALDH1A1L3MBTL1MAPK1CYP3A4TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5134150-A | Administering diaryl-substituted imidazothiazoles; antiarthritic agents | SMITHKLINE BEECHAM CORPORATION (US) | 1992-07-28 | — | — | US | disclosed |