Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | TERT | O14746 | 1/20 | 0.39 |
| ▸ | S100B | P04271 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.35 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9738632 | 0.92 | ALDH1A1 (0.42) | ALDH1A1TDP1MAPTMEN1KMT2A | |
| SCHEMBL8064164 | 0.86 | ALDH1A1 (0.44) | ALDH1A1TDP1MAPTMEN1KMT2A | |
| SCHEMBL10893246 | 0.81 | MAPK1 (0.40) | ALDH1A1TDP1MAPTMEN1KMT2A | |
| SCHEMBL9480308 | 0.79 | CNR2 (0.35) | ALDH1A1MAPTMEN1KMT2AGAA | |
| SCHEMBL9739215 | 0.78 | APP (0.41) | ALDH1A1TDP1MAPTMEN1KMT2A | |
| SCHEMBL9739246 | 0.78 | APP (0.41) | ALDH1A1MEN1KMT2APGRHSD17B10 | |
| SCHEMBL9509481 | 0.75 | ALDH1A1 (0.40) | ALDH1A1TDP1MAPTMEN1KMT2A | |
| SCHEMBL10350058 | 0.75 | CYP3A4 (0.47) | ALDH1A1TDP1MEN1KMT2AGAA | |
| SCHEMBL5925342 | 0.75 | APP (0.46) | ALDH1A1MAPTMEN1KMT2ATSHR | |
| SCHEMBL10449130 | 0.74 | APP (0.46) | ALDH1A1TDP1MAPTTHRBTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1025107-B1 | PHOTOCHROMIC COMPOUNDS | JAMES ROBINSON LTD (GB) | 2002-08-07 | — | — | EP | claimed |
| US-6303673-B1 | FOR OPTICAL ELEMENTS | JAMES ROBINSON LIMITED (GB) | 2001-10-16 | — | — | US | claimed |
| EP-0336879-A1 | Meso-tetraphenylporphyrin complex compounds,process for their preparation and pharmaceuticals containing them | SCHERING AKTIENGESELLSCHAFT (DE) | 1989-10-11 | — | — | EP | disclosed |