SCHEMBL9738640

SCHEMBL9738640

CCCC(N1CCOCC1)N1CCOCC1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.39
ALDH1A1 P00352 3/20 0.39
LMNA P02545 2/20 0.39
MAPT P10636 1/20 0.39
HPGD P15428 1/20 0.39
RAB9A P51151 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
TSHR P16473 2/20 0.38
MEN1 O00255 2/20 0.34
KCNH2 Q12809 3/20 0.33
KCNA5 P22460 2/20 0.33
USP2 O75604 1/20 0.33
HTT P42858 2/20 0.32
POLB P06746 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
GAA P10253 1/20 0.31
SLC6A2 P23975 2/20 0.31
SLC6A4 P31645 1/20 0.31
SLC6A3 Q01959 1/20 0.31
CYP1A2 P05177 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7104710 0.85 KCNH2 (0.41) KMT2AALDH1A1LMNAMAPTHPGD
SCHEMBL9740019 0.83 KCNH2 (0.43) KMT2AALDH1A1LMNAMAPTHPGD
SCHEMBL9738468 0.83 KCNH2 (0.43) KMT2AALDH1A1LMNAMAPTHPGD
SCHEMBL16919618 0.81 KMT2A (0.39) KMT2AALDH1A1LMNAMAPTHPGD
SCHEMBL1994023 0.80 ALDH1A1 (0.41) KMT2AALDH1A1LMNAMAPTHPGD
SCHEMBL232222 0.79 KMT2A (0.47) KMT2AALDH1A1LMNAMAPTHPGD
SCHEMBL8737569 0.79 KMT2A (0.47) KMT2AALDH1A1LMNAMAPTHPGD
SCHEMBL2086387 0.77 TSHR (0.42) KMT2AALDH1A1LMNAMAPTHPGD
SCHEMBL8557598 0.77 KMT2A (0.37) KMT2AALDH1A1LMNAMAPTHPGD
SCHEMBL231163 0.77 KMT2A (0.37) KMT2AALDH1A1LMNAMAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5120731-A For use as oxygen carriers in blood substitutes KALIE-CHEMIE AG (DE) 1992-06-09 US disclosed
US-4070416-A POLYFUNCTIONAL ISOCYANATES AND EPOXIDES, ISOCYANURATE-OXAZOLIDOLE POLYMERS HITACHI, LTD. (JA) 1978-01-24 US disclosed