Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8737569 | 1.00 | KMT2A (0.47) | KMT2AMEN1ALDH1A1LMNAMAPT | |
| Pyrrole SCHEMBL23500101 | 0.87 | KMT2A (0.43) | KMT2AMEN1ALDH1A1LMNAMAPT | |
| SCHEMBL10677620 | 0.85 | KMT2A (0.44) | KMT2AMEN1ALDH1A1LMNAMAPT | |
| SCHEMBL24590304 | 0.85 | KMT2A (0.44) | KMT2AMEN1ALDH1A1LMNAMAPT | |
| SCHEMBL19481173 | 0.84 | KMT2A (0.43) | KMT2AMEN1ALDH1A1LMNAMAPT | |
| SCHEMBL5659817 | 0.84 | KMT2A (0.43) | KMT2AMEN1ALDH1A1LMNAMAPT | |
| SCHEMBL28245667 | 0.84 | KMT2A (0.43) | KMT2AMEN1ALDH1A1LMNAMAPT | |
| SCHEMBL20363959 | 0.84 | KMT2A (0.43) | KMT2AMEN1ALDH1A1LMNAMAPT | |
| SCHEMBL19630484 | 0.83 | KDM4E (0.38) | KMT2AMEN1TSHRGAA | |
| SCHEMBL11573468 | 0.83 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104945470-A | Tripeptide epoxy ketone compound constructed by heterocycle as well as preparation method and application thereof | UNIV ZHEJIANG | 2015-09-30 | — | — | CN | claimed |
| US-20240216515-A1 | COMPOSITIONS AND METHODS FOR TARGETED DELIVERY TO CELLS | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM | 2024-07-04 | — | — | US | disclosed |
| US-20230357240-A1 | NOVEL N-HETEROCYCLIC BET BROMODOMAIN INHIBITOR, AND PREPARATION METHOD THEREOF AND MEDICAL USE THEREOF | CHENGDU EASTON BIOPHARMACEUTICALS CO LTD (CN) | 2023-11-09 | — | — | US | disclosed |
| US-20230312498-A1 | NON-ATP/CATALYTIC SITE p38 MITOGEN ACTIVATED PROTEIN KINASE INHIBITORS | UNIVERSITY OF MARYLAND, BALTIMORE | 2023-10-05 | — | — | US | disclosed |
| WO-2023154499-A1 | EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF | BIOGEN MA INC. (US) | 2023-08-17 | — | — | WO | disclosed |
| US-11718595-B2 | Non-ATP/catalytic site p38 Mitogen Activated Protein Kinase inhibitors | UNIVERSITY OF MARYLAND, BALTIMORE (US) | 2023-08-08 | — | — | US | disclosed |
| US-20230192688-A1 | PROLYL HYDROXYLASE DOMAIN-CONTAINING PROTEIN (PHD) INHIBITORS AND USES THEREOF | INSILICO MEDICINE IP LIMITED (HK) | 2023-06-22 | — | — | US | disclosed |
| US-11524959-B1 | Indole and azaindole inhibitors of pad enzymes | BRISTOL-MYERS SQUIBB COMPANY (US) | 2022-12-13 | — | — | US | disclosed |
| US-RE48887-E1 | RNA interference compositions and methods for malignant tumors | NITTO DENKO CORPORATION (JP) | 2022-01-11 | — | — | US | disclosed |
| US-20210317160-A1 | 3,4-THIAZOLO-STEROIDS AND METHODS OF MAKING AND USING THE SAME | Arkansas State University - Jonesboro | 2021-10-14 | — | — | US | disclosed |
| US-7863454-B2 | 3-substituted-6-aryl pyridines | NOVARTIS INTERNATIONAL PHARMACEUTICAL LTD. (BM) | 2011-01-04 | — | — | US | disclosed |
| CN-100582087-C | 2-amino-bicyclo [3.1.0] hexane-2, 6-dicarboxylic acid ester derivatives | TAISHO PHARMACEUTICAL CO LTD | 2010-01-20 | — | — | CN | disclosed |
| US-20090306408-A1 | 2-Amino-Bicyclo (3.1.0) Hexane-2,6-Dicarboxylic Ester Derivative | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2009-12-10 | — | — | US | disclosed |
| EP-2123630-A1 | 2-Amino-bicyclo[3.1.0]hexane-2,6-dicarboxylic ester derivative | Taisho Pharmaceutical Co. Ltd. (JP) | 2009-11-25 | — | — | EP | disclosed |
| US-20090176980-A1 | 3-Substituted-6-Aryl Pyridines | NOVARTIS INTERNATIONAL PHARMACEUTICAL LTD. (BM) | 2009-07-09 | — | — | US | disclosed |
| US-7342115-B2 | Binding antagonist and arylpyridine for antiinflammatory agents, cardiovascular disorders and antagonist or agonist and for immunology | NEUROGEN CORPORATION (US) | 2008-03-11 | — | — | US | disclosed |
| US-20070021394-A1 | 2-Aminobicyclo[3.1.0]hexane-2,6-dicarboxylic ester derivative | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2007-01-25 | — | — | US | disclosed |
| CN-1812960-A | 2-amino-bicyclo [3.1.0] hexane-2, 6-dicarboxylic acid ester derivatives | TAISHO PHARMACEUTICAL CO LTD (JP) | 2006-08-02 | — | — | CN | disclosed |
| EP-1637517-A1 | 2-AMINOBICYCLO 3.1.0 HEXANE-2,6-DICARBOXYLIC ESTER DERIVATIVE | Taisho Pharmaceutical Co. Ltd. (JP) | 2006-03-22 | — | — | EP | disclosed |
| US-4992150-A | Telomer with alpha-olefin;oil and fuel additive | NIPPON OIL CO, LTD. (JP) | 1991-02-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230192688-A1 | PROLYL HYDROXYLASE DOMAIN-CONTAINING PROTEIN (PHD) INHIBITORS AND USES THEREOF | EGLN3, EGLN2, EGLN1 | KMT2A 736/4885MEN1 4748/4885ALDH1A1 1538/4885 |
| US-20210317160-A1 | 3,4-THIAZOLO-STEROIDS AND METHODS OF MAKING AND USING THE SAME | HSD17B7, HSD17B3, NR3C2 | KMT2A 4424/4885MEN1 461/4885ALDH1A1 826/4885 |
| US-20090176980-A1 | 3-Substituted-6-Aryl Pyridines | C3AR1, C5AR1, C5AR2 | KMT2A 3960/4885MEN1 3563/4885ALDH1A1 1966/4885 |
| US-20090306408-A1 | 2-Amino-Bicyclo (3.1.0) Hexane-2,6-Dicarboxylic Ester Derivative | GRIK4, GRIN2D, GRIN2C | KMT2A 1954/4885MEN1 3095/4885ALDH1A1 720/4885 |
| US-20070021394-A1 | 2-Aminobicyclo[3.1.0]hexane-2,6-dicarboxylic ester derivative | GRIN2C, GRIK4, GRIN2B | KMT2A 2151/4885MEN1 3213/4885ALDH1A1 479/4885 |
| US-20230312498-A1 | NON-ATP/CATALYTIC SITE p38 MITOGEN ACTIVATED PROTEIN KINASE INHIBITORS | MAPK1, MAPK8, MAPK4 | KMT2A 3519/4885MEN1 4385/4885ALDH1A1 4111/4885 |
| US-11524959-B1 | Indole and azaindole inhibitors of pad enzymes | PADI4, PADI1, PADI2 | KMT2A 154/4885MEN1 3682/4885ALDH1A1 101/4885 |
| US-20240216515-A1 | COMPOSITIONS AND METHODS FOR TARGETED DELIVERY TO CELLS | PNLIP, LIPA, PHOSPHO1 | KMT2A 4697/4885MEN1 2255/4885ALDH1A1 4241/4885 |
| US-11718595-B2 | Non-ATP/catalytic site p38 Mitogen Activated Protein Kinase inhibitors | MAPK1, MAPK8, MAPK4 | KMT2A 3519/4885MEN1 4385/4885ALDH1A1 4111/4885 |
| US-20230357240-A1 | NOVEL N-HETEROCYCLIC BET BROMODOMAIN INHIBITOR, AND PREPARATION METHOD THEREOF AND MEDICAL USE THEREOF | BRD4, BRD1, BET1 | KMT2A 282/4885MEN1 1007/4885ALDH1A1 3744/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.