Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NSD2 | O96028 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.31 |
| ▸ | PTGES | O14684 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9737886 | 0.86 | TLK2 (0.32) | NSD2ABL1PPARGRIN1L3MBTL1 | |
| SCHEMBL9739750 | 0.85 | BRD4 (0.35) | NSD2ABL1PPARGRIN1L3MBTL1 | |
| SCHEMBL9737102 | 0.84 | CNR2 (0.37) | NPSR1MEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL9732959 | 0.82 | NSD2 (0.31) | NSD2ABL1PPARGRIN1L3MBTL1 | |
| SCHEMBL9735940 | 0.78 | KDM4E (0.34) | NPSR1PTGESMEN1KMT2AKDM4E | |
| SCHEMBL9734747 | 0.78 | NSD2 (0.32) | NSD2ABL1PPARGRIN1L3MBTL1 | |
| SCHEMBL9737040 | 0.72 | NPSR1 (0.30) | NSD2ABL1PPARGRIN1L3MBTL1 | |
| SCHEMBL9732950 | 0.67 | PDPK1 (0.33) | — | |
| SCHEMBL9147909 | 0.67 | NR1H4 (0.33) | NPSR1KDM4EMAPT | |
| SCHEMBL9736448 | 0.65 | ALOX5 (0.35) | NPSR1MEN1KMT2ASMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5143924-A | OXODIHYDROPYRIDYL CHROMAN DERIVATIVES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1992-09-01 | — | — | US | disclosed |