Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 4/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.34 |
| ▸ | RAB9A | P51151 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9733057 | 0.85 | PDPK1 (0.38) | CNR2ALOX5PDPK1CNR1SMN1; SMN2 | |
| SCHEMBL9738641 | 0.84 | NSD2 (0.33) | SMN1; SMN2MAPTKDM4EMEN1KMT2A | |
| SCHEMBL9736448 | 0.81 | ALOX5 (0.35) | CNR2ALOX5PDPK1CNR1SMN1; SMN2 | |
| SCHEMBL9740084 | 0.80 | CNR2 (0.36) | CNR2ALOX5PDPK1CNR1SMN1; SMN2 | |
| SCHEMBL9735336 | 0.76 | ALOX5 (0.36) | CNR2ALOX5PDPK1CNR1SMN1; SMN2 | |
| SCHEMBL9738703 | 0.71 | CNR2 (0.38) | CNR2ALOX5CNR1SMN1; SMN2RAB9A | |
| SCHEMBL7853544 | 0.70 | CA1 (0.50) | SMN1; SMN2RAB9AMAPTALDH1A1KDM4E | |
| SCHEMBL9738536 | 0.68 | ALDH1A1 (0.39) | CNR2SMN1; SMN2RAB9AALDH1A1POLB | |
| SCHEMBL9732959 | 0.67 | NSD2 (0.31) | — | |
| SCHEMBL9735584 | 0.67 | ALOX5 (0.34) | ALOX5SMN1; SMN2RAB9AMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5143924-A | OXODIHYDROPYRIDYL CHROMAN DERIVATIVES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1992-09-01 | — | — | US | disclosed |