Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.30 |
| ▸ | PTGES | O14684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9740084 | 0.84 | CNR2 (0.36) | KDM4ENPC1RAB9ALMNAALDH1A1 | |
| SCHEMBL9733370 | 0.82 | KDM4E (0.34) | KDM4ENPC1RAB9ALMNAALDH1A1 | |
| SCHEMBL9738641 | 0.78 | NSD2 (0.33) | KDM4ENPSR1MEN1KMT2APTGES | |
| SCHEMBL9735400 | 0.78 | KDM4E (0.35) | KDM4ENPC1RAB9ALMNAALDH1A1 | |
| SCHEMBL9736236 | 0.73 | KDM4E (0.33) | KDM4ENPC1RAB9ALMNAALDH1A1 | |
| SCHEMBL9733368 | 0.69 | ALOX5 (0.36) | KDM4ENPC1RAB9AALDH1A1MEN1 | |
| SCHEMBL9372031 | 0.68 | KDM4E (0.33) | KDM4ENPC1RAB9ALMNAALDH1A1 | |
| SCHEMBL9147909 | 0.66 | NR1H4 (0.33) | KDM4ENPSR1NR1H4 | |
| SCHEMBL9737886 | 0.65 | TLK2 (0.32) | KDM4EALDH1A1 | |
| SCHEMBL9736485 | 0.64 | IDO1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5143924-A | OXODIHYDROPYRIDYL CHROMAN DERIVATIVES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1992-09-01 | — | — | US | disclosed |