Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 5/20 | 0.46 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HRH2 | P25021 | 1/20 | 0.35 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6726435 | 0.93 | LMNA (0.42) | TLR7TLR8LMNANPSR1ALDH1A1 | |
| SCHEMBL6723871 | 0.92 | TLR7 (0.52) | TLR7TLR8LMNANPSR1ALDH1A1 | |
| SCHEMBL10589469 | 0.84 | TLR7 (0.52) | TLR7TLR8LMNANPSR1ALDH1A1 | |
| SCHEMBL6730743 | 0.83 | TLR7 (0.41) | TLR7TLR8LMNANPSR1ALDH1A1 | |
| SCHEMBL6724391 | 0.81 | TLR7 (0.40) | TLR7TLR8LMNANPSR1ALDH1A1 | |
| SCHEMBL6719567 | 0.81 | TLR7 (0.43) | TLR7TLR8LMNANPSR1ALDH1A1 | |
| SCHEMBL5808827 | 0.79 | LMNA (0.53) | TLR7TLR8LMNANPSR1ALDH1A1 | |
| SCHEMBL8565615 | 0.79 | TSHR (0.47) | TLR7TLR8LMNANPSR1ALDH1A1 | |
| SCHEMBL6719520 | 0.79 | TLR7 (0.42) | TLR7TLR8LMNANPSR1ALDH1A1 | |
| SCHEMBL4314545 | 0.79 | ALDH1A1 (0.39) | TLR7TLR8LMNANPSR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992015582-A1 | 1-SUBSTITUTED, 2-SUBSTITUTED 1H-IMIDAZO[4,5-c]QUINOLIN-4-AMINES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1992-09-17 | — | — | WO | disclosed |