Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | GPR88 | Q9GZN0 | 2/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | ATP1A1 | P05023 | 1/20 | 0.30 |
| ▸ | ATP1B1 | P05026 | 1/20 | 0.30 |
| ▸ | ATP1A3 | P13637 | 1/20 | 0.30 |
| ▸ | ATP1B2 | P14415 | 1/20 | 0.30 |
| ▸ | ATP1A2 | P50993 | 1/20 | 0.30 |
| ▸ | ATP1B3 | P54709 | 1/20 | 0.30 |
| ▸ | FXYD2 | P54710 | 1/20 | 0.30 |
| ▸ | ATP1A4 | Q13733 | 1/20 | 0.30 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.30 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20445442 | 0.71 | ADRB2 (0.44) | MEN1KMT2ASIGMAR1HTTTAAR1 | |
| SCHEMBL19545888 | 0.66 | TAAR1 (0.44) | MEN1KMT2ASIGMAR1TAAR1AOC3 | |
| SCHEMBL6215535 | 0.61 | AOC3 (0.53) | ALDH1A1MEN1KMT2ASIGMAR1AOC3 | |
| SCHEMBL5078354 | 0.61 | AOC3 (0.53) | ALDH1A1MEN1KMT2ASIGMAR1AOC3 | |
| SCHEMBL6215546 | 0.61 | AOC3 (0.53) | ALDH1A1MEN1KMT2ASIGMAR1AOC3 | |
| SCHEMBL13431479 | 0.59 | MEN1 (0.45) | ALDH1A1HDAC6SMN1; SMN2MEN1KMT2A | |
| SCHEMBL13431478 | 0.59 | MEN1 (0.45) | ALDH1A1HDAC6SMN1; SMN2MEN1KMT2A | |
| SCHEMBL10159454 | 0.59 | TAAR1 (0.46) | ALDH1A1SIGMAR1TAAR1AOC3LMNA | |
| SCHEMBL10939739 | 0.58 | SIGMAR1 (0.52) | ALDH1A1SMN1; SMN2MEN1KMT2ASIGMAR1 | |
| SCHEMBL3627329 | 0.58 | LMNA (0.50) | MEN1KMT2ATAAR1AOC3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5116856-A | AMINOETHYLTHIAZOLE AND AMINOETHYLOXAZOLE DERIVATIVES | AKZO N.V. (NL) | 1992-05-26 | — | — | US | disclosed |
| EP-0385525-A1 | Aminoethylthiazole and aminoethyloxazole derivatives | Akzo Nobel N.V. (NL) | 1990-09-05 | — | — | EP | disclosed |