Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 5/20 | 0.41 |
| ▸ | CA1 | P00915 | 5/20 | 0.41 |
| ▸ | CA9 | Q16790 | 5/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 7/20 | 0.39 |
| ▸ | MAOA | P21397 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 4/20 | 0.37 |
| ▸ | MGAM | O43451 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28231902 | 0.81 | CA12 (0.41) | MAPTMEN1LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL8532102 | 0.78 | NQO1 (0.50) | MEN1KMT2ASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL9065504 | 0.76 | CA12 (0.57) | MAPTMEN1LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL472165 | 0.76 | CA12 (0.57) | MAPTMEN1LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL3846804 | 0.76 | MAPT (0.42) | MAPTMEN1LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL9230402 | 0.75 | ALDH1A1 (0.42) | MAPTMEN1LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL920851 | 0.75 | MAPT (0.41) | MAPTMEN1LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL15066907 | 0.75 | MAPT (0.41) | MAPTMEN1LMNAKMT2ASMN1; SMN2 | |
| 1,4-Diallyloxybenzene SCHEMBL302448 | 0.74 | CA12 (0.63) | MAPTMEN1LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL19856490 | 0.74 | CA12 (0.47) | MAPTMEN1LMNAKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5134150-A | Administering diaryl-substituted imidazothiazoles; antiarthritic agents | SMITHKLINE BEECHAM CORPORATION (US) | 1992-07-28 | — | — | US | disclosed |