Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.40 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.40 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | METAP2 | P50579 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11179575 | 0.84 | SMN1; SMN2 (0.52) | KMT2ASMN1; SMN2MEN1GAATSHR | |
| SCHEMBL28720392 | 0.83 | TP53 (0.41) | KMT2ASMN1; SMN2MEN1GAATP53 | |
| SCHEMBL2453510 | 0.78 | TSHR (0.52) | KMT2ASMN1; SMN2MEN1TP53TSHR | |
| SCHEMBL8964823 | 0.78 | TSHR (0.52) | KMT2ASMN1; SMN2MEN1TP53TSHR | |
| SCHEMBL7239333 | 0.78 | TP53 (0.45) | KMT2ASMN1; SMN2MEN1TP53TSHR | |
| SCHEMBL8263643 | 0.74 | ALDH1A1 (0.44) | KMT2ASMN1; SMN2GAANCOA3ALDH1A1 | |
| SCHEMBL11713544 | 0.74 | SMN1; SMN2 (0.50) | KMT2ASMN1; SMN2MEN1GAATSHR | |
| SCHEMBL25403607 | 0.72 | TSHR (0.57) | KMT2ASMN1; SMN2TP53TSHRNPC1 | |
| SCHEMBL31331854 | 0.72 | KMT2A (0.49) | KMT2ASMN1; SMN2MEN1GAATSHR | |
| SCHEMBL783597 | 0.71 | KMT2A (0.63) | KMT2ASMN1; SMN2MEN1GAATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5134150-A | Administering diaryl-substituted imidazothiazoles; antiarthritic agents | SMITHKLINE BEECHAM CORPORATION (US) | 1992-07-28 | — | — | US | disclosed |