SCHEMBL9738854

SCHEMBL9738854

O[C@]1(c2ccc(Cl)s2)CCCC[C@@H]1Br

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.37
GAA P10253 2/20 0.37
HTT P42858 2/20 0.37
KMT2A Q03164 2/20 0.37
HPGD P15428 2/20 0.37
PSEN1 P49768 6/20 0.35
PSEN2 P49810 6/20 0.35
APH1B Q8WW43 6/20 0.35
NCSTN Q92542 6/20 0.35
APH1A Q96BI3 6/20 0.35
PSENEN Q9NZ42 6/20 0.35
MEN1 O00255 1/20 0.35
RAB9A P51151 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
SLC6A2 P23975 1/20 0.33
SLC6A4 P31645 1/20 0.33
TRPA1 O75762 1/20 0.32
F10 P00742 1/20 0.32
HCAR3 P49019 1/20 0.31
HCAR2 Q8TDS4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9738856 1.00 ALDH1A1 (0.37) ALDH1A1GAAHTTKMT2AHPGD
SCHEMBL9738849 1.00 ALDH1A1 (0.37) ALDH1A1GAAHTTKMT2AHPGD
SCHEMBL9736578 0.72 IDO1 (0.30)
SCHEMBL9734640 0.72 IDO1 (0.30)
SCHEMBL9736581 0.72 IDO1 (0.30)
SCHEMBL9734637 0.72 IDO1 (0.30)
SCHEMBL9734636 0.72 IDO1 (0.30)
SCHEMBL9733887 0.71 IDO1 (0.32) ALDH1A1GAAHTTKMT2AHPGD
SCHEMBL9733890 0.71 IDO1 (0.32) ALDH1A1GAAHTTKMT2AHPGD
SCHEMBL11018236 0.71 TRPA1 (0.33) TRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5091539-A Reacting an ozolyl cycloalkanone with Grignard reagent or alkali metal compound SHIONOGI & CO., LTD. (JP) 1992-02-25 US disclosed
EP-0152031-A2 Azolyl cycloalkanol derivatives and agricultural fungicides SHIONOGI & CO., LTD. (JP) 1985-08-21 EP disclosed