Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | RAF1 | P04049 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 5/20 | 0.32 |
| ▸ | RAB9A | P51151 | 5/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9739629 | 0.90 | ALDH1A1 (0.35) | ALDH1A1MAPK1KMT2AMEN1KDM4E | |
| SCHEMBL10591266 | 0.88 | MEN1 (0.32) | ALDH1A1MAPK1KMT2AMEN1 | |
| SCHEMBL9738311 | 0.88 | KMT2A (0.32) | ALDH1A1MAPK1KMT2AMEN1KDM4E | |
| SCHEMBL9738882 | 0.88 | ELANE (0.33) | ALDH1A1MAPK1KMT2AMEN1MAPT | |
| SCHEMBL9739103 | 0.86 | CA12 (0.38) | ALDH1A1MAPK1KMT2AMEN1NPSR1 | |
| SCHEMBL9874689 | 0.83 | SMN1; SMN2 (0.41) | ALDH1A1MAPK1KMT2AMEN1LMNA | |
| SCHEMBL9739114 | 0.76 | HPD (0.38) | ALDH1A1MAPK1KMT2AMEN1KDM4E | |
| SCHEMBL9872626 | 0.73 | SMN1; SMN2 (0.39) | ALDH1A1LMNAMAPTHPGDNPC1 | |
| SCHEMBL9740555 | 0.73 | AKR1C3 (0.45) | ALDH1A1MAPK1KDM4EMAPTNPC1 | |
| SCHEMBL9738636 | 0.72 | FLT1 (0.39) | ALDH1A1MAPK1KMT2AMEN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5089046-A | Herbicides or miticide | SANDOZ LTD. (CH) | 1992-02-18 | — | — | US | disclosed |
| EP-0336898-A2 | Substituted aryl or heteroaryl diones | SANDOZ AG (CH) | 1989-10-11 | — | — | EP | disclosed |