Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.31 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.31 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9739629 | 0.88 | ALDH1A1 (0.35) | CA1CA2CA9ALDH1A1MAPT | |
| SCHEMBL9738873 | 0.86 | ALDH1A1 (0.39) | ALDH1A1MAPTMAPK1SMN1; SMN2NPC1 | |
| SCHEMBL9738882 | 0.86 | ELANE (0.33) | ALDH1A1MAPTMAPK1KMT2AMEN1 | |
| SCHEMBL10591266 | 0.86 | MEN1 (0.32) | ALDH1A1MAPK1KMT2AMEN1 | |
| SCHEMBL9738311 | 0.86 | KMT2A (0.32) | ALDH1A1MAPTMAPK1SMN1; SMN2NPC1 | |
| SCHEMBL9874629 | 0.85 | HPGD (0.42) | ALDH1A1CES2MAPTSMN1; SMN2NPC1 | |
| SCHEMBL9739114 | 0.71 | HPD (0.38) | ALDH1A1MAPTMAPK1SMN1; SMN2KMT2A | |
| SCHEMBL9740555 | 0.70 | AKR1C3 (0.45) | ALDH1A1MAPTMAPK1SMN1; SMN2NPC1 | |
| SCHEMBL9874689 | 0.70 | SMN1; SMN2 (0.41) | ALDH1A1MAPTMAPK1SMN1; SMN2NPC1 | |
| SCHEMBL9738636 | 0.67 | FLT1 (0.39) | ALDH1A1MAPTMAPK1SMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5089046-A | Herbicides or miticide | SANDOZ LTD. (CH) | 1992-02-18 | — | — | US | disclosed |
| EP-0336898-A2 | Substituted aryl or heteroaryl diones | SANDOZ AG (CH) | 1989-10-11 | — | — | EP | disclosed |