Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.35 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9738647 | 0.85 | HSD11B1 (0.43) | RXFP1NPC1POLBHSD11B1MEN1 | |
| SCHEMBL9739008 | 0.83 | SMN1; SMN2 (0.55) | MEN1KMT2AHTTSMN1; SMN2CYP1A2 | |
| SCHEMBL9738615 | 0.83 | CHRM5 (0.46) | NPC1POLBMEN1KMT2AHTT | |
| SCHEMBL9739497 | 0.83 | MAPT (0.46) | NPC1POLBMEN1KMT2AHTT | |
| SCHEMBL9741164 | 0.83 | CHRM5 (0.49) | NPC1POLBHSD11B1MEN1KMT2A | |
| SCHEMBL9738811 | 0.82 | NPC1 (0.35) | RXFP1NPC1POLBMEN1KMT2A | |
| SCHEMBL9740223 | 0.80 | CHRM5 (0.48) | NPC1SMN1; SMN2CYP3A4TSHRCHRM5 | |
| SCHEMBL9738592 | 0.80 | HSD11B1 (0.41) | NPC1POLBHSD11B1MEN1KMT2A | |
| SCHEMBL9742164 | 0.80 | CHRM5 (0.47) | NPC1POLBMEN1KMT2AHTT | |
| SCHEMBL9740111 | 0.78 | SLC6A2 (0.43) | NPC1POLBMEN1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992016529-A1 | NOVEL ISOINDOLE DERIVATIVES AND MEDICAMENTS CONTAINING THEM | BOEHRINGER MANNHEIM GMBH (DE) | 1992-10-01 | — | — | WO | disclosed |