Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMS | P04818 | 2/20 | 0.76 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.76 |
| ▸ | MEN1 | O00255 | 1/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.76 |
| ▸ | POLB | P06746 | 1/20 | 0.76 |
| ▸ | GAA | P10253 | 1/20 | 0.76 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.76 |
| ▸ | HPGD | P15428 | 1/20 | 0.76 |
| ▸ | TSHR | P16473 | 1/20 | 0.76 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.76 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.76 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.76 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.76 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.57 |
| ▸ | DHFR | P00374 | 5/20 | 0.52 |
| ▸ | ATIC | P31939 | 4/20 | 0.52 |
| ▸ | GART | P22102 | 3/20 | 0.52 |
| ▸ | SHMT1 | P34896 | 1/20 | 0.46 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14947039 | 0.94 | TYMS (0.67) | TYMSKDM4EMEN1ALDH1A1POLB | |
| SCHEMBL20716790 | 0.90 | TYMS (0.62) | TYMSKDM4EMEN1ALDH1A1POLB | |
| SCHEMBL29853494 | 0.90 | TYMS (0.76) | TYMSKDM4EMEN1ALDH1A1POLB | |
| SCHEMBL13658559 | 0.90 | TYMS (0.76) | TYMSKDM4EMEN1ALDH1A1POLB | |
| SCHEMBL434591 | 0.90 | TYMS (0.76) | TYMSKDM4EMEN1ALDH1A1POLB | |
| SCHEMBL24513791 | 0.89 | TYMS (0.65) | TYMSKDM4EMEN1ALDH1A1POLB | |
| SCHEMBL21361683 | 0.88 | TYMS (0.59) | TYMSKDM4EMEN1ALDH1A1POLB | |
| Folic Acid SCHEMBL182653 | 0.88 | TYMS (0.87) | TYMSKDM4EMEN1ALDH1A1POLB | |
| Folic Acid SCHEMBL28212675 | 0.88 | TYMS (0.85) | TYMSKDM4EMEN1ALDH1A1POLB | |
| Folic Acid SCHEMBL3877 | 0.87 | TYMS (1.00) | TYMSKDM4EMEN1ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230285561-A1 | Targeting Microbubbles | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2023-09-14 | — | — | US | disclosed |
| US-11642410-B2 | Targeting microbubbles | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2023-05-09 | — | — | US | disclosed |
| US-11642410-B2 | Targeting microbubbles | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2023-05-09 | — | — | US | disclosed |
| US-10357565-B2 | Targeting microbubbles | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2019-07-23 | — | — | US | disclosed |
| US-20190038749-A1 | TARGETING MICROBUBBLES | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2019-02-07 | — | — | US | disclosed |
| US-20160367669-A1 | TARGETING MICROBUBBLES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2016-12-22 | — | — | US | disclosed |
| US-20160367669-A1 | TARGETING MICROBUBBLES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2016-12-22 | — | — | US | disclosed |
| US-20130123781-A1 | TARGETING MICROBUBBLES | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2013-05-16 | — | — | US | disclosed |
| US-20130123781-A1 | TARGETING MICROBUBBLES | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2013-05-16 | — | — | US | disclosed |
| US-20110020242-A1 | HIGH-DENSITY LIPOPROTEIN-LIKE PEPTIDE-PHOSPHOLIPID SCAFFOLD (\"HPPS\") NANOPARTICLES | UNIVERSITY HEALTH NETWORK (CA) | 2011-01-27 | — | — | US | disclosed |
| EP-2229411-A1 | HIGH-DENSITY LIPOPROTEIN-LIKE PEPTIDE-PHOSPHOLIPID SCAFFOLD (\"HPPS\") NANOPARTICLES | University Health Network (CA) | 2010-09-22 | — | — | EP | disclosed |
| WO-2009073984-A1 | HIGH-DENSITY LIPOPROTEIN-LIKE PEPTIDE-PHOSPHOLIPID SCAFFOLD ('HPPS') NANOPARTICLES | UNIVERSITY HEALTH NETWORK (CA) | 2009-06-18 | — | — | WO | disclosed |
| US-20080253960-A1 | Lipoprotein-Based Nanoplatforms | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA CENTER FOR TECHNOLOGY TRANSFER (US) | 2008-10-16 | — | — | US | disclosed |
| EP-1778298-A2 | LIPOPROTEIN NANOPLATFORMS | The Trustees of The University of Pennsylvania (US) | 2007-05-02 | — | — | EP | disclosed |
| WO-2006073419-A2 | LIPOPROTEIN NANOPLATFORMS | ZHENG GANG (US) | 2006-07-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130123781-A1 | TARGETING MICROBUBBLES | PGF, EDNRB, FLT4 | TYMS 1681/4885KDM4E 3320/4885MEN1 1071/4885 |
| US-20190038749-A1 | TARGETING MICROBUBBLES | PGF, EDNRB, FLT4 | TYMS 1681/4885KDM4E 3320/4885MEN1 1071/4885 |
| US-10357565-B2 | Targeting microbubbles | PGF, EDNRB, FLT4 | TYMS 1681/4885KDM4E 3320/4885MEN1 1071/4885 |
| US-20230285561-A1 | Targeting Microbubbles | PGF, EDNRB, FLT4 | TYMS 1681/4885KDM4E 3320/4885MEN1 1071/4885 |
| US-20160367669-A1 | TARGETING MICROBUBBLES | PGF, EDNRB, FLT4 | TYMS 1681/4885KDM4E 3320/4885MEN1 1071/4885 |
| US-11642410-B2 | Targeting microbubbles | PGF, EDNRB, FLT4 | TYMS 1681/4885KDM4E 3320/4885MEN1 1071/4885 |
| US-20080253960-A1 | Lipoprotein-Based Nanoplatforms | LDLR, APOL1, LRP6 | TYMS 4811/4885KDM4E 4504/4885MEN1 4253/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.