Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB4A | P04350 | 8/20 | 0.57 |
| ▸ | TUBB | P07437 | 8/20 | 0.57 |
| ▸ | TUBA3C | P0DPH7 | 8/20 | 0.57 |
| ▸ | TUBA1B | P68363 | 8/20 | 0.57 |
| ▸ | TUBA4A | P68366 | 8/20 | 0.57 |
| ▸ | TUBB4B | P68371 | 8/20 | 0.57 |
| ▸ | TUBB3 | Q13509 | 8/20 | 0.57 |
| ▸ | TUBB2A | Q13885 | 8/20 | 0.57 |
| ▸ | TUBB8 | Q3ZCM7 | 8/20 | 0.57 |
| ▸ | TUBA3E | Q6PEY2 | 8/20 | 0.57 |
| ▸ | TUBA1A | Q71U36 | 8/20 | 0.57 |
| ▸ | TUBA1C | Q9BQE3 | 8/20 | 0.57 |
| ▸ | TUBB6 | Q9BUF5 | 8/20 | 0.57 |
| ▸ | TUBB2B | Q9BVA1 | 8/20 | 0.57 |
| ▸ | TUBB1 | Q9H4B7 | 8/20 | 0.57 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9741988 | 0.90 | TUBB4A (0.52) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL9742331 | 0.79 | TUBB1 (0.58) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL9739054 | 0.78 | IDO1 (0.44) | CA2CALM1 | |
| SCHEMBL9740472 | 0.78 | GAA (0.59) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL9739685 | 0.76 | PDE10A (0.44) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL8910416 | 0.75 | PTGS2 (0.70) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL9740073 | 0.74 | TUBB4A (0.51) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL9740060 | 0.73 | TUBB4A (0.47) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL9740017 | 0.73 | DHFR (0.42) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL29066052 | 0.73 | TUBB1 (1.00) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5175157-A | Cardiovascular disorders | BOEHRINGER INGELHEIM GMBH (DE) | 1992-12-29 | — | — | US | disclosed |