SCHEMBL9739325

SCHEMBL9739325

CC(C)(ON1C(C)(C)CC(C(CCCCCCCC(=O)O)(C(=O)O)C2CC(C)(C)N(OC(C)(C)c3ccccc3)C(C)(C)C2)CC1(C)C)c1ccccc1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGER3 P43115 4/20 0.34
PTGER4 P35408 2/20 0.34
PTGER2 P43116 4/20 0.33
TSHR P16473 3/20 0.33
KMT2A Q03164 2/20 0.33
RBP4 P02753 1/20 0.33
NR5A2 O00482 1/20 0.33
TBXA2R P21731 2/20 0.32
MEN1 O00255 1/20 0.32
GAA P10253 1/20 0.32
PDK2 Q15119 1/20 0.32
KDM4E B2RXH2 1/20 0.32
ALDH1A1 P00352 1/20 0.32
ALOX15 P16050 1/20 0.32
MAPK1 P28482 1/20 0.32
CASP1 P29466 1/20 0.32
HTT P42858 1/20 0.32
HSD17B10 Q99714 1/20 0.32
S1PR5 Q9H228 1/20 0.32
MAPT P10636 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4809149 0.86 PTGER3 (0.33) PTGER3PTGER4PTGER2TSHRKMT2A
SCHEMBL9737855 0.84 TBXAS1 (0.35) TSHRALDH1A1TBXAS1
SCHEMBL6492997 0.84 PTGFR (0.37) PTGER3TSHRKMT2ANR5A2TBXA2R
SCHEMBL1264361 0.82 FFAR1 (0.34) PTGER3PTGER4PTGER2NR5A2TBXA2R
SCHEMBL209037 0.82 MAPT (0.37) PTGER4PTGER2TSHRKMT2AMEN1
SCHEMBL1263978 0.82 KMT2A (0.51) PTGER3TSHRKMT2ANR5A2TBXA2R
SCHEMBL4813400 0.81 FFAR4 (0.33) PTGER3PTGER4PTGER2TSHRKMT2A
SCHEMBL15911950 0.81 ALDH1A1 (0.33) TSHRKMT2AMEN1ALDH1A1ALOX15
SCHEMBL993913 0.80 ALDH1A1 (0.35) TSHRKMT2AMEN1ALDH1A1ALOX15
SCHEMBL9244463 0.80 PPARA (0.36) TSHRKMT2AMEN1GAAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5096950-A N-alkoxypiperidines CIBA-GEIGY CORPORATION (US) 1992-03-17 US claimed
US-5004770-A Light, heat, and oxygen resistant CIBA-GEIGY CORPORATION (US) 1991-04-02 US claimed
US-5124378-A Resin containign N-Hydroxyl hindered amine oxidative and light stabilizers CIBA-GEIGY CORPORATION (US) 1992-06-23 US disclosed
US-5112890-A Piperidine compound with oxygen bonded to ring nitrogen CIBA-GEIGY CORPORATION (US) 1992-05-12 US disclosed
US-5096950-A N-alkoxypiperidines CIBA-GEIGY CORPORATION (US) 1992-03-17 US disclosed
US-5004770-A Light, heat, and oxygen resistant CIBA-GEIGY CORPORATION (US) 1991-04-02 US disclosed