Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER3 | P43115 | 4/20 | 0.33 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.33 |
| ▸ | PTGER2 | P43116 | 4/20 | 0.32 |
| ▸ | NR5A2 | O00482 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 3/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4813400 | 0.88 | FFAR4 (0.33) | PTGER3PTGER4PTGER2ALDH1A1TSHR | |
| SCHEMBL9739325 | 0.86 | PTGER3 (0.34) | PTGER3PTGER4PTGER2NR5A2ALDH1A1 | |
| SCHEMBL209037 | 0.85 | MAPT (0.37) | PTGER4PTGER2ALDH1A1CYP3A4TSHR | |
| SCHEMBL39320 | 0.84 | TBXAS1 (0.31) | — | |
| SCHEMBL6492997 | 0.82 | PTGFR (0.37) | PTGER3NR5A2TBXA2RPDK2TSHR | |
| SCHEMBL9784227 | 0.81 | PTGFR (0.40) | PTGER3PTGER4PTGER2NR5A2ALDH1A1 | |
| SCHEMBL995190 | 0.81 | GPR84 (0.33) | ALDH1A1ESR1TSHRALOX15HSD17B10 | |
| SCHEMBL1263978 | 0.81 | KMT2A (0.51) | PTGER3NR5A2ALDH1A1TBXA2RESR1 | |
| SCHEMBL7114359 | 0.80 | PTGFR (0.34) | PTGER2NR5A2ALDH1A1PDK2PTGER1 | |
| SCHEMBL38997 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120164162-A1 | METHODS IN CELL CULTURES, AND RELATED INVENTIONS, EMPLOYING CERTAIN ADDITIVES | BASF SE (DE) | 2012-06-28 | — | — | US | claimed |
| US-8859235-B2 | Methods in cell cultures, and related inventions, employing certain additives | BASF SE (DE) | 2014-10-14 | — | — | US | disclosed |
| US-20120164162-A1 | METHODS IN CELL CULTURES, AND RELATED INVENTIONS, EMPLOYING CERTAIN ADDITIVES | BASF SE (DE) | 2012-06-28 | — | — | US | disclosed |
| US-7390904-B2 | Hydrogen peroxide catalyzed process for the preparation of sterically hindered N-hydrocarbyloxyamines | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2008-06-24 | — | — | US | disclosed |
| US-20050014948-A1 | Hydrogen peroxide catalyzed process for the preparation of sterically hindered N-hydrocarbyloxyamines | CIBA SPECIALTY CHEMICALS CORP. | 2005-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050014948-A1 | Hydrogen peroxide catalyzed process for the preparation of sterically hindered N-hydrocarbyloxyamines | HAO2, SOD1, PPOX | PTGER3 4648/4885PTGER4 3973/4885PTGER2 4170/4885 |
| US-20120164162-A1 | METHODS IN CELL CULTURES, AND RELATED INVENTIONS, EMPLOYING CERTAIN ADDITIVES | BBOX1, NEFM, NQO1 | PTGER3 2599/4885PTGER4 1456/4885PTGER2 2518/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.