Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPBWR1 | P48145 | 4/20 | 0.45 |
| ▸ | HTT | P42858 | 8/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 6/20 | 0.41 |
| ▸ | LMNA | P02545 | 5/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 6/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | MITF | O75030 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9674153 | 0.91 | NPBWR1 (0.58) | NPBWR1MEN1KMT2AMAPTMAPK1 | |
| SCHEMBL9672434 | 0.88 | RAB9A (0.36) | NPBWR1HTTALDH1A1NPSR1LMNA | |
| SCHEMBL6999341 | 0.86 | MAPT (0.42) | NPBWR1ALDH1A1NPSR1RAB9AMEN1 | |
| SCHEMBL7005110 | 0.85 | TSHR (0.36) | NPBWR1HTTALDH1A1NPSR1LMNA | |
| SCHEMBL7005108 | 0.85 | TSHR (0.36) | NPBWR1HTTALDH1A1NPSR1LMNA | |
| SCHEMBL7001314 | 0.84 | RAB9A (0.52) | NPBWR1HTTALDH1A1NPSR1LMNA | |
| SCHEMBL9674408 | 0.81 | NPC1 (0.33) | NPBWR1HTTALDH1A1NPSR1CYP2C19 | |
| SCHEMBL9674412 | 0.81 | NPC1 (0.33) | NPBWR1HTTALDH1A1NPSR1CYP2C19 | |
| SCHEMBL7000441 | 0.78 | KAT2B (0.43) | NPBWR1ALDH1A1NPSR1RAB9AMEN1 | |
| SCHEMBL7001264 | 0.72 | KAT2B (0.47) | ALDH1A1NPSR1RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992012137-A1 | NOVEL 3(2H)-PYRIDAZINONES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PROCESS FOR PREPARING SAME | Richter Gedeon Vegyészeti Gyár Rt. (HU) | 1992-07-23 | — | — | WO | disclosed |