Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | NPBWR1 | P48145 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 8/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 6/20 | 0.41 |
| ▸ | LMNA | P02545 | 5/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | MITF | O75030 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | RECQL | P46063 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7001264 | 0.86 | KAT2B (0.47) | RAB9ANPC1KMT2AMEN1ALDH1A1 | |
| SCHEMBL7003258 | 0.85 | NPC1 (0.45) | RAB9ANPC1KMT2AMEN1HTT | |
| SCHEMBL7003256 | 0.85 | NPC1 (0.45) | RAB9ANPC1KMT2AMEN1HTT | |
| SCHEMBL6998936 | 0.85 | RAB9A (0.50) | RAB9ANPC1KMT2AMEN1NPBWR1 | |
| SCHEMBL9739364 | 0.84 | NPBWR1 (0.45) | RAB9ANPC1KMT2AMEN1NPBWR1 | |
| SCHEMBL6999530 | 0.78 | KAT2B (0.48) | RAB9ANPC1KMT2AMEN1ALDH1A1 | |
| SCHEMBL7002772 | 0.77 | RAB9A (0.51) | RAB9ANPC1KMT2AMEN1HTT | |
| SCHEMBL7006298 | 0.77 | ALDH1A1 (0.46) | RAB9ANPC1KMT2AMEN1ALDH1A1 | |
| SCHEMBL7001161 | 0.76 | NPC1 (0.44) | RAB9ANPC1KMT2AMEN1NPBWR1 | |
| SCHEMBL7001162 | 0.76 | NPC1 (0.44) | RAB9ANPC1KMT2AMEN1NPBWR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6602865-B1 | Pyridazino(4,5-b)(1,5)oxazepinone, -thiazepinone and -diazepinone compounds | IVAX DRUG RESEARCH INSTITUTE, LTD. (HU) | 2003-08-05 | — | — | US | disclosed |
| EP-1129097-B1 | NOVEL TYPE CONDENSED PYRIDAZINONE COMPOUNDS | GYOGYSZERKUTATO INTEZET (HU) | 2003-01-29 | — | — | EP | disclosed |
| EP-1129097-A1 | NOVEL TYPE CONDENSED PYRIDAZINONE COMPOUNDS | GYOGYSZERKUTATO INTEZET KFT. (HU) | 2001-09-05 | — | — | EP | disclosed |
| WO-2000027851-A1 | NOVEL TYPE CONDENSED PYRIDAZINONE COMPOUNDS | Gyógyszerkutató Intézet Kft. (HU) | 2000-05-18 | — | — | WO | disclosed |