Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.53 |
| ▸ | LTA4H | P09960 | 11/20 | 0.52 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | PPARA | Q07869 | 1/20 | 0.49 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.48 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9713562 | 0.86 | FFAR1 (0.64) | FFAR1LTA4HPLA2G4B | |
| SCHEMBL1752763 | 0.82 | FFAR1 (0.70) | FFAR1LTA4H | |
| SCHEMBL9856987 | 0.81 | LMNA (0.55) | ABCB1NPC1RAB9ANR1H4 | |
| SCHEMBL8890454 | 0.81 | FFAR1 (0.59) | FFAR1LTA4HNR1H4 | |
| SCHEMBL6187602 | 0.80 | NR1H4 (0.64) | NPC1MAPK1RAB9ASMN1; SMN2PLA2G4B | |
| SCHEMBL7914606 | 0.80 | NPC1 (0.56) | ABCB1NPC1MAPK1RAB9ASMN1; SMN2 | |
| SCHEMBL8887581 | 0.80 | FFAR1 (0.58) | FFAR1LTA4HNR1H4 | |
| SCHEMBL8890073 | 0.80 | FFAR1 (0.58) | FFAR1LTA4HNR1H4 | |
| SCHEMBL8888760 | 0.80 | FFAR1 (0.58) | FFAR1LTA4HNR1H4 | |
| SCHEMBL19825762 | 0.79 | FFAR1 (0.61) | FFAR1LTA4HNR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5116853-A | SRS-Antagonist, Antiallergens | MASE TOSHIYASU (JP) | 1992-05-26 | — | — | US | disclosed |
| US-4994479-A | Antagonists of SRS-A(slow reacting substance of anaphylaxis); antiallergens, antiischemic agents | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1991-02-19 | — | — | US | disclosed |
| EP-0218728-A1 | PHENYLENE DERIVATIVES | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1987-04-22 | — | — | EP | disclosed |
| WO-1986005779-A1 | PHENYLENE DERIVATIVES | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1986-10-09 | — | — | WO | disclosed |