Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 7/20 | 0.64 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.56 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.56 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.55 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.55 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.54 |
| ▸ | LTA4H | P09960 | 1/20 | 0.54 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.54 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.51 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.51 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.51 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.51 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.51 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.51 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1747055 | 0.86 | FFAR1 (0.74) | FFAR1S1PR1S1PR3S1PR5PLA2G4B | |
| SCHEMBL9739385 | 0.86 | ABCB1 (0.55) | FFAR1PLA2G4BLTA4H | |
| SCHEMBL27588900 | 0.82 | FFAR1 (0.69) | FFAR1FFAR4PTGER1PTGER4PTGER3 | |
| SCHEMBL9713432 | 0.82 | LTA4H (0.57) | FFAR1S1PR1FFAR4S1PR3S1PR5 | |
| SCHEMBL1746597 | 0.79 | FFAR1 (1.00) | FFAR1S1PR1FFAR4S1PR3S1PR5 | |
| SCHEMBL9857414 | 0.78 | NR1H4 (0.59) | FFAR1PLA2G4BCYSLTR2CYSLTR1 | |
| SCHEMBL9856969 | 0.78 | ALDH1A1 (0.58) | FFAR1S1PR1S1PR3S1PR5 | |
| SCHEMBL11262209 | 0.78 | HTR1A (0.58) | LTA4HEPHX2PTGER1PTGER4PTGER3 | |
| SCHEMBL27606882 | 0.78 | FFAR1 (0.68) | FFAR1FFAR4PTGER1PTGER4PTGER3 | |
| SCHEMBL4656572 | 0.77 | FFAR1 (0.97) | FFAR1S1PR1FFAR4S1PR3S1PR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5140046-A | Slow reacting substance of anaphylaxis antagonists | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1992-08-18 | — | — | US | claimed |
| US-4994479-A | Antagonists of SRS-A(slow reacting substance of anaphylaxis); antiallergens, antiischemic agents | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1991-02-19 | — | — | US | disclosed |
| EP-0218728-A1 | PHENYLENE DERIVATIVES | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1987-04-22 | — | — | EP | disclosed |
| WO-1986005779-A1 | PHENYLENE DERIVATIVES | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1986-10-09 | — | — | WO | disclosed |