Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 8/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9739808 | 0.93 | HRH3 (0.41) | HRH3KCNH2 | |
| SCHEMBL9740374 | 0.93 | HRH3 (0.41) | HRH3KCNH2 | |
| SCHEMBL9739061 | 0.88 | ACHE (0.40) | SIGMAR1 | |
| SCHEMBL9739652 | 0.84 | ADRA1B (0.45) | HRH3 | |
| SCHEMBL9740254 | 0.83 | HRH3 (0.44) | HRH3 | |
| SCHEMBL9739322 | 0.82 | HRH3 (0.42) | HRH3 | |
| SCHEMBL9206673 | 0.82 | PRMT5 (0.38) | SIGMAR1 | |
| SCHEMBL9739164 | 0.82 | HRH3 (0.51) | HRH3 | |
| SCHEMBL9740331 | 0.81 | HRH3 (0.51) | HRH3 | |
| SCHEMBL9217084 | 0.81 | ADRA1B (0.46) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5175157-A | Cardiovascular disorders | BOEHRINGER INGELHEIM GMBH (DE) | 1992-12-29 | — | — | US | disclosed |