Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 6/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | USP2 | O75604 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 8/20 | 0.38 |
| ▸ | HTR2B | P41595 | 5/20 | 0.38 |
| ▸ | HTR2A | P28223 | 5/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7440822 | 0.77 | HTR2C (0.52) | MEN1KMT2AALDH1A1HTR2CHTR2B | |
| SCHEMBL10296104 | 0.76 | MEN1 (0.65) | MEN1KMT2AKDM4EMAPK1HSD17B10 | |
| SCHEMBL9216049 | 0.75 | MEN1 (0.48) | MEN1KMT2AKDM4EMAPK1HSD17B10 | |
| SCHEMBL9204844 | 0.73 | MEN1 (0.49) | MEN1KMT2AHTR2CHTR2BHTR2A | |
| SCHEMBL9208378 | 0.72 | MEN1 (0.47) | MEN1KMT2AKDM4EMAPK1HSD17B10 | |
| SCHEMBL9207673 | 0.72 | MEN1 (0.47) | MEN1KMT2AALOX15MAPT | |
| SCHEMBL9216770 | 0.71 | MEN1 (0.46) | MEN1KMT2AKDM4EMAPK1HSD17B10 | |
| SCHEMBL9209711 | 0.70 | MEN1 (0.50) | MEN1KMT2AKDM4EMAPK1HSD17B10 | |
| SCHEMBL9207494 | 0.68 | PARP1 (0.48) | MEN1KMT2AHTR2CHTR2BHTR2A | |
| SCHEMBL9666453 | 0.66 | KMT2A (0.55) | MEN1KMT2AKDM4EMAPK1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5175157-A | Cardiovascular disorders | BOEHRINGER INGELHEIM GMBH (DE) | 1992-12-29 | — | — | US | disclosed |