Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 3/20 | 0.33 |
| ▸ | EDNRA | P25101 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9738134 | 0.91 | AGTR1 (0.35) | AGTR1FAAHALDH1A1MGLLAGTR2 | |
| SCHEMBL9737978 | 0.90 | AGTR1 (0.34) | AGTR1FAAHALDH1A1MGLLAGTR2 | |
| SCHEMBL9738129 | 0.89 | AGTR1 (0.35) | AGTR1AGTR2 | |
| SCHEMBL9738516 | 0.87 | AGTR1 (0.36) | AGTR1AGTR2 | |
| SCHEMBL9738276 | 0.86 | AGTR1 (0.38) | AGTR1AGTR2 | |
| SCHEMBL9738035 | 0.85 | AGTR1 (0.41) | AGTR1 | |
| SCHEMBL9738653 | 0.85 | TRPV1 (0.35) | ALDH1A1 | |
| SCHEMBL9738272 | 0.85 | AGTR1 (0.35) | AGTR1EDNRAAGTR2 | |
| SCHEMBL9738616 | 0.85 | SLC33A1 (0.36) | AGTR1EDNRAAGTR2 | |
| SCHEMBL9738503 | 0.84 | TRPV1 (0.36) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992005161-A1 | 1,3,5-TRISUBSTITUTED-1,2,4-TRIAZOLE COMPOUNDS FOR TREATMENT OF CIRCULATORY DISORDERS | G.D. SEARLE & CO. (US) | 1992-04-02 | — | — | WO | claimed |
| WO-1992005161-A1 | 1,3,5-TRISUBSTITUTED-1,2,4-TRIAZOLE COMPOUNDS FOR TREATMENT OF CIRCULATORY DISORDERS | G.D. SEARLE & CO. (US) | 1992-04-02 | — | — | WO | disclosed |