Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.35 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25280107 | 0.78 | HSD11B1 (0.34) | ALDH1A1MEN1KMT2A | |
| SCHEMBL9740256 | 0.77 | SMN1; SMN2 (0.40) | MAPTLMNACNR1KDM4EMAPK1 | |
| SCHEMBL9739624 | 0.73 | LMNA (0.46) | MAPTLMNAKDM4EMAPK1NPSR1 | |
| SCHEMBL8746025 | 0.73 | MAPT (0.37) | MAPTLMNAKDM4EMAPK1NPSR1 | |
| SCHEMBL5250851 | 0.72 | IDO1 (0.37) | DDB1CRBNTDP1NOTUMALDH1A1 | |
| SCHEMBL11838548 | 0.72 | IDO1 (0.37) | DDB1CRBNKDM4ETDP1NOTUM | |
| SCHEMBL7242656 | 0.70 | CYP1A2 (0.56) | KDM4EALDH1A1MEN1CYP1A2POLB | |
| SCHEMBL3890627 | 0.69 | POLB (0.55) | MAPTKDM4ETDP1ALDH1A1MEN1 | |
| SCHEMBL14994078 | 0.69 | AR (0.36) | DDB1CRBNSMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL4188982 | 0.69 | IDO1 (0.35) | DDB1CRBNKDM4ETDP1NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5153227-A | Treatment of diabetes and galactosemia complications | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-10-06 | — | — | US | disclosed |