Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9739732 | 0.87 | CYP1A2 (0.50) | KMT2AMEN1MAPTKDM4ERECQL | |
| SCHEMBL9741185 | 0.87 | KMT2A (0.47) | KMT2AMEN1MAPTKDM4ERECQL | |
| SCHEMBL6182511 | 0.79 | KMT2A (0.47) | KMT2AMEN1MAPTKDM4ERECQL | |
| SCHEMBL3455095 | 0.78 | MAPT (0.55) | KMT2AMEN1MAPTKDM4ERECQL | |
| SCHEMBL9739607 | 0.78 | S1PR2 (0.35) | KMT2AKDM4ECYP1A2 | |
| SCHEMBL9740214 | 0.78 | CYP1A2 (0.61) | KMT2AMAPTKDM4EHTTGAA | |
| SCHEMBL22804462 | 0.77 | MAPT (0.48) | KMT2AMEN1MAPTKDM4ERECQL | |
| SCHEMBL10853491 | 0.76 | MAPT (0.44) | KMT2AMEN1MAPTKDM4ERECQL | |
| SCHEMBL9749074 | 0.76 | MAPT (0.41) | KMT2AMEN1MAPTKDM4ERECQL | |
| SCHEMBL10850245 | 0.75 | MAPT (0.47) | KMT2AMEN1MAPTKDM4ERECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5126454-A | PROCESS FOR THE PREPARATION OF SULPHONYLISOUREAS | BAYER AKTIENGESELLSCHAFT (DE) | 1992-06-30 | — | — | US | disclosed |