Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9749082 | 0.81 | MEN1 (0.41) | KMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL9739707 | 0.76 | KMT2A (0.47) | MAPTKMT2AMEN1GAAMAPK1 | |
| SCHEMBL10504747 | 0.72 | MEN1 (0.46) | MAPTKMT2AMEN1GAAMAPK1 | |
| SCHEMBL10504753 | 0.72 | MEN1 (0.46) | MAPTKMT2AMEN1GAAMAPK1 | |
| SCHEMBL3455095 | 0.68 | MAPT (0.55) | MAPTKMT2AMEN1GAAMAPK1 | |
| SCHEMBL22804462 | 0.66 | MAPT (0.48) | MAPTKMT2AMEN1GAAMAPK1 | |
| SCHEMBL20034295 | 0.66 | MAPT (0.44) | MAPTKMT2AMEN1GAAMAPK1 | |
| SCHEMBL9741185 | 0.66 | KMT2A (0.47) | MAPTKMT2AMEN1KDM4ERECQL | |
| SCHEMBL9739732 | 0.66 | CYP1A2 (0.50) | MAPTKMT2AMEN1KDM4ERECQL | |
| SCHEMBL9749081 | 0.66 | KMT2A (0.42) | MAPTKMT2AMEN1MAPK1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5126454-A | PROCESS FOR THE PREPARATION OF SULPHONYLISOUREAS | BAYER AKTIENGESELLSCHAFT (DE) | 1992-06-30 | — | — | US | disclosed |