SCHEMBL9739607

SCHEMBL9739607

COC(=N)Nc1nc(Cl)cc(Cl)n1

nearest known ligand 0.36

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
S1PR2 O95136 1/20 0.35
CYP1A2 P05177 2/20 0.35
KMT2A Q03164 1/20 0.35
CASP1 P29466 1/20 0.34
KDM4E B2RXH2 1/20 0.33
BCHE P06276 1/20 0.31
ACHE P22303 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9741185 0.89 KMT2A (0.47) CYP1A2KMT2ACASP1KDM4E
SCHEMBL9741145 0.88 CYP1A2 (0.53) S1PR2CYP1A2KMT2AKDM4E
SCHEMBL9739707 0.78 KMT2A (0.47) CYP1A2KMT2AKDM4E
SCHEMBL9740214 0.76 CYP1A2 (0.61) CYP1A2KMT2AKDM4E
SCHEMBL11022815 0.75 S1PR2 (0.38) S1PR2CYP1A2KMT2ACASP1
SCHEMBL9749082 0.74 MEN1 (0.41) KMT2AKDM4E
SCHEMBL140276 0.71 CYP1A2 (0.55) S1PR2CYP1A2KMT2ACASP1
SCHEMBL4451761 0.71 LMNA (0.32)
SCHEMBL9739732 0.71 CYP1A2 (0.50) CYP1A2KMT2AKDM4E
SCHEMBL9316067 0.70 S1PR2 (0.40) S1PR2CYP1A2KMT2ACASP1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5126454-A PROCESS FOR THE PREPARATION OF SULPHONYLISOUREAS BAYER AKTIENGESELLSCHAFT (DE) 1992-06-30 US disclosed