Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | CLK2 | P49760 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | TOP1 | P11387 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4469284 | 0.77 | KCNH2 (0.35) | KCNH2KDM4EHPGDALDH1A1POLB | |
| SCHEMBL4459458 | 0.76 | KCNH2 (0.34) | KCNH2KDM4EHPGDALDH1A1LMNA | |
| SCHEMBL8564944 | 0.72 | KCNH2 (0.70) | KCNH2KDM4EHPGDALDH1A1LMNA | |
| SCHEMBL8567530 | 0.72 | KCNH2 (0.70) | KCNH2KDM4EHPGDALDH1A1LMNA | |
| SCHEMBL4558410 | 0.72 | — | — | |
| SCHEMBL8567534 | 0.71 | KCNH2 (0.57) | KCNH2KDM4EHPGDALDH1A1LMNA | |
| SCHEMBL7024322 | 0.71 | DRD2 (0.33) | KCNH2KDM4EHPGDALDH1A1POLB | |
| SCHEMBL2541190 | 0.67 | IKBKB (0.44) | — | |
| SCHEMBL2541184 | 0.67 | IKBKB (0.44) | — | |
| SCHEMBL10785290 | 0.67 | MAOA (0.38) | KDM4EHPGDALDH1A1LMNAALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5157128-A | Antibacterial agents | WARNER-LAMBERT COMPANY (US) | 1992-10-20 | — | — | US | disclosed |