Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | CLK2 | P49760 | 1/20 | 0.33 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.30 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.30 |
| ▸ | GSK3B | P49841 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1985195 | 0.73 | MEN1 (0.31) | MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL4469284 | 0.72 | KCNH2 (0.35) | KCNH2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL9739807 | 0.71 | KCNH2 (0.36) | KCNH2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL4459458 | 0.69 | KCNH2 (0.34) | KCNH2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL8664577 | 0.69 | ALDH1A1 (0.45) | KDM4EALDH1A1HPGDHSD17B10TDP1 | |
| SCHEMBL4558410 | 0.69 | — | — | |
| SCHEMBL3816673 | 0.68 | KCNH2 (0.34) | KCNH2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL8668032 | 0.67 | MEN1 (0.33) | KDM4EALDH1A1HPGDHSD17B10POLB | |
| SCHEMBL10556130 | 0.64 | ACKR3 (0.30) | — | |
| SCHEMBL6215417 | 0.63 | HCRTR2 (0.33) | KCNH2KDM4EALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1343766-A1 | CYCLIZATION PROCESS STEP IN THE MAKING OF QUINOLONES AND NAPHTHYRIDINES | THE PROCTER & GAMBLE COMPANY (US) | 2003-09-17 | — | — | EP | disclosed |
| WO-2002048113-A1 | CYCLIZATION PROCESS STEP IN THE MAKING OF QUINOLONES AND NAPHTHYRIDINES | THE PROCTER & GAMBLE COMPANY (US) | 2002-06-20 | — | — | WO | disclosed |