Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9740196 | 1.00 | REN (0.41) | RENBACE1 | |
| SCHEMBL7314705 | 0.93 | REN (0.52) | REN | |
| SCHEMBL9849789 | 0.87 | GAA (0.47) | RENBACE1 | |
| SCHEMBL9849779 | 0.87 | GAA (0.47) | RENBACE1 | |
| SCHEMBL7309940 | 0.83 | CA1 (0.44) | REN | |
| SCHEMBL9725745 | 0.83 | CA1 (0.44) | REN | |
| SCHEMBL7295314 | 0.83 | CA1 (0.44) | REN | |
| SCHEMBL9725752 | 0.83 | CA1 (0.44) | REN | |
| SCHEMBL7295320 | 0.83 | CA1 (0.44) | REN | |
| SCHEMBL7277211 | 0.83 | HSPA5 (0.36) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5104869-A | Renin inhibitors | AMERICAN CYANAMID COMPANY (US) | 1992-04-14 | — | — | US | disclosed |
| EP-0427939-A2 | Renin inhibitors | AMERICAN CYANAMID COMPANY (US) | 1991-05-22 | — | — | EP | disclosed |