Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 8/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | FAAH | O00519 | 3/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.31 |
| ▸ | MGLL | Q99685 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9734985 | 0.90 | CASP1 (0.37) | CASP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL9736565 | 0.82 | NPSR1 (0.36) | ALDH1A1PKMSMN1; SMN2 | |
| SCHEMBL9735726 | 0.80 | FAAH (0.31) | FAAHPKMSMN1; SMN2MGLL | |
| SCHEMBL10862091 | 0.76 | PKM (0.37) | CASP1ALDH1A1FAAHPKMSMN1; SMN2 | |
| SCHEMBL13969328 | 0.76 | PKM (0.37) | CASP1ALDH1A1FAAHPKMSMN1; SMN2 | |
| SCHEMBL13946279 | 0.74 | PKM (0.35) | ALDH1A1FAAHPKMSMN1; SMN2MAPT | |
| SCHEMBL12442504 | 0.74 | PKM (0.35) | ALDH1A1FAAHPKMSMN1; SMN2MAPT | |
| SCHEMBL13969329 | 0.74 | PKM (0.37) | ALDH1A1FAAHPKMSMN1; SMN2MGLL | |
| SCHEMBL10691169 | 0.73 | FAAH (0.37) | CASP1ALDH1A1FAAHMAPTMGLL | |
| SCHEMBL10790502 | 0.73 | FAAH (0.37) | CASP1ALDH1A1FAAHMAPTMGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5138050-A | 6-amido-1-methyl carbapenems | MERCK & CO., INC. (US) | 1992-08-11 | — | — | US | disclosed |
| WO-1990000170-A1 | NOVEL 6-AMIDO-1-METHYLCARBAPENEMS | MERCK & CO., INC. (US) | 1990-01-11 | — | — | WO | disclosed |