SCHEMBL9740522

CC(C)[C@H](N)C(=O)N(C(=O)CCc1cccnc1)[C@@H](Cc1ccccc1)C(O)C(O)[C@H](Cc1ccccc1)N(C(=O)CCc1cccnc1)C(=O)[C@@H](N)C(C)C

nearest known ligand 0.48

Predicted protein targets (top 12)

	gene	UniProt	supporting neighbours	confidence
▸	LMNA	P02545	1/20	0.48

▸	ANPEP	P15144	2/20	0.41

▸	ERAP2	Q6P179	1/20	0.41

▸	ERAP1	Q9NZ08	1/20	0.41

▸	TBXAS1	P24557	11/20	0.41

▸	CYP1A2	P05177	1/20	0.39

▸	CYP3A4	P08684	1/20	0.39

▸	CYP2C9	P11712	1/20	0.39

▸	CYP2C19	P33261	1/20	0.39

▸	KCNA5	P22460	1/20	0.38

▸	MAPT	P10636	1/20	0.37

▸	KDM4E	B2RXH2	1/20	0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL6447519	1.00	LMNA (0.48)	LMNAANPEPERAP2ERAP1TBXAS1
SCHEMBL7269049	0.99	LMNA (0.47)	LMNAANPEPERAP2ERAP1TBXAS1
SCHEMBL6449597	0.84	CYP1A2 (0.44)	CYP1A2CYP3A4CYP2C19MAPTKDM4E
SCHEMBL6448340	0.83	LMNA (0.47)	LMNAANPEPERAP2ERAP1TBXAS1
SCHEMBL6449476	0.83	LMNA (0.47)	LMNAANPEPERAP2ERAP1TBXAS1
SCHEMBL6446316	0.83	LMNA (0.47)	LMNAANPEPERAP2ERAP1TBXAS1
SCHEMBL9741503	0.83	LMNA (0.47)	LMNAANPEPERAP2ERAP1TBXAS1
SCHEMBL7269409	0.82	CYP1A2 (0.45)	CYP1A2CYP3A4CYP2C19MAPTKDM4E
SCHEMBL7268965	0.82	CYP3A4 (0.46)	LMNAANPEPERAP2ERAP1TBXAS1
SCHEMBL7270435	0.82	L3MBTL1 (0.47)	LMNACYP1A2CYP3A4CYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-5142056-A	Human immunodeficiency virus protease inhibitor	ABBOTT LABORATORIES (US)	1992-08-25	—	—	US	disclosed