Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 20/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9740589 | 1.00 | REN (0.54) | REN | |
| SCHEMBL9849618 | 0.90 | REN (0.48) | REN | |
| SCHEMBL9740006 | 0.90 | REN (0.48) | REN | |
| SCHEMBL9740000 | 0.90 | REN (0.48) | REN | |
| SCHEMBL9740255 | 0.90 | REN (0.48) | REN | |
| SCHEMBL9740471 | 0.84 | REN (0.66) | REN | |
| SCHEMBL9740465 | 0.84 | REN (0.66) | REN | |
| SCHEMBL9741069 | 0.84 | REN (0.47) | REN | |
| SCHEMBL9741074 | 0.84 | REN (0.47) | REN | |
| SCHEMBL7370857 | 0.80 | REN (0.54) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5104869-A | Renin inhibitors | AMERICAN CYANAMID COMPANY (US) | 1992-04-14 | — | — | US | disclosed |
| EP-0427939-A2 | Renin inhibitors | AMERICAN CYANAMID COMPANY (US) | 1991-05-22 | — | — | EP | disclosed |