Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 17/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | CTSD | P07339 | 1/20 | 0.44 |
| ▸ | CTSE | P14091 | 1/20 | 0.44 |
| ▸ | CTSS | P25774 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9741074 | 1.00 | REN (0.47) | RENGAAL3MBTL1CTSDCTSE | |
| SCHEMBL9705257 | 0.89 | REN (0.46) | RENCTSDCTSECTSSCTSK | |
| SCHEMBL9705262 | 0.89 | REN (0.46) | RENCTSDCTSECTSSCTSK | |
| SCHEMBL9849779 | 0.87 | GAA (0.47) | RENGAAL3MBTL1CTSDCTSS | |
| SCHEMBL9849789 | 0.87 | GAA (0.47) | RENGAAL3MBTL1CTSDCTSS | |
| SCHEMBL9740591 | 0.84 | REN (0.54) | REN | |
| SCHEMBL9740589 | 0.84 | REN (0.54) | REN | |
| SCHEMBL9749328 | 0.83 | REN (0.53) | RENCTSDCTSE | |
| SCHEMBL9740697 | 0.82 | REN (0.41) | RENCTSK | |
| SCHEMBL9740699 | 0.82 | REN (0.41) | RENCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5104869-A | Renin inhibitors | AMERICAN CYANAMID COMPANY (US) | 1992-04-14 | — | — | US | disclosed |