Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.48 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | CA12 | O43570 | 3/20 | 0.43 |
| ▸ | CA2 | P00918 | 3/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA7 | P43166 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CA4 | P22748 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.43 |
| ▸ | CA6 | P23280 | 1/20 | 0.43 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11349953 | 1.00 | LMNA (0.54) | LMNAMAPK1GABRA1GABRB2TSHR | |
| SCHEMBL31107080 | 1.00 | LMNA (0.54) | LMNAMAPK1GABRA1GABRB2TSHR | |
| SCHEMBL974064 | 1.00 | LMNA (0.54) | LMNAMAPK1GABRA1GABRB2TSHR | |
| SCHEMBL7522933 | 0.98 | LMNA (0.52) | LMNAMAPK1GABRA1GABRB2TSHR | |
| Hydrochloric Acid SCHEMBL1375900 | 0.98 | LMNA (0.52) | LMNAMAPK1GABRA1GABRB2TSHR | |
| SCHEMBL7522050 | 0.98 | LMNA (0.52) | LMNAMAPK1GABRA1GABRB2TSHR | |
| Ammonia Solution, Strong SCHEMBL7523599 | 0.98 | LMNA (0.52) | LMNAMAPK1GABRA1GABRB2TSHR | |
| SCHEMBL7522924 | 0.98 | LMNA (0.52) | LMNAMAPK1GABRA1GABRB2TSHR | |
| Water SCHEMBL7529368 | 0.98 | LMNA (0.52) | LMNAMAPK1GABRA1GABRB2TSHR | |
| SCHEMBL7522058 | 0.98 | LMNA (0.52) | LMNAMAPK1GABRA1GABRB2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 142 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260092029-A1 | LIGAND-ENABLED SCALABLE C-H HYDROXYLATION OF BENZOIC AND PHENYLACETIC ACIDS AT ROOM TEMPERATURE | SCRIPPS RESEARCH INST (US) | 2026-04-02 | — | — | US | claimed |
| EP-4584236-A1 | LIGAND-ENABLED SCALABLE C-H HYDROXYLATION OF BENZOIC AND PHENYLACETIC ACIDS AT ROOM TEMPERATURE | The Scripps Research Institute (US) | 2025-07-16 | — | — | EP | claimed |
| WO-2024054881-A1 | LIGAND-ENABLED SCALABLE C-H HYDROXYLATION OF BENZOIC AND PHENYLACETIC ACIDS AT ROOM TEMPERATURE | THE SCRIPPS RESEARCH INSTITUTE (US) | 2024-03-14 | — | — | WO | claimed |
| CN-115036064-A | Wear-resistant cable and preparation method thereof | 张妮 | 2022-09-09 | — | — | CN | claimed |
| CN-109467502-B | Method for splitting mandelic acid compound enantiomer | 湖南科技大学 | 2021-07-30 | — | — | CN | claimed |
| EP-2029515-B1 | USE OF METAL COMPLEXES COMPRISING A LIGAND DERIVED FROM 2-ARYL-2-HYDROXYACETIC ACID AND A DIVALENT OR TRIVALENT METAL CATION FOR THE TREATMENT OF METAL DEFICIENCY IN PLANTS. | WEYLCHEM LAMOTTE (FR) | 2016-03-09 | — | — | EP | claimed |
| CN-102603368-B | Metal complexes comprising ligands derived from 2-aryl-2-hydroxyacetic acid and divalent or trivalent metal cations and use thereof | CLARIANT SPECIALTY FINE CHEM F | 2014-06-25 | — | — | CN | claimed |
| US-8372176-B2 | Metal complexes comprising a ligand derived from 2-aryl-2-hydroxyacetic acid and a divalent or trivalent metal cation, and their use | CLARIANT SPECIALTY FINE CHEMICALS (FRANCE) (FR) | 2013-02-12 | — | — | US | claimed |
| US-20100288004-A1 | Metal Complexes Comprising A Ligand Derived From 2-Aryl-2-Hydroxyacetic Acid And A Divalent Or Trivalent Metal Cation, And Their Use | CLARIANT SPECIALTY FINE CHEMICALS (FRANCE) (FR) | 2010-11-18 | — | — | US | claimed |
| CN-101454268-A | Metal complexes comprising ligands derived from 2-aryl-2-hydroxyacetic acid and divalent or trivalent metal cations and use thereof | CLARIANT SPECIALTY FINE CHEM (FR) | 2009-06-10 | — | — | CN | claimed |
| US-6359172-B1 | Method of preparing 2- and 4-hydroxymandelic acid | GERARD KESSELS SOCIEDAD ANONIMA, S.A. (ES) | 2002-03-19 | — | — | US | claimed |
| EP-0987245-B1 | A method of preparing 2- and 4-hydroxymandelic acid | GERARD KESSELS S A (ES) | 2002-03-13 | — | — | EP | claimed |
| EP-0987245-A1 | A method of preparing 2- and 4-hydroxymandelic acid | Gerard Kessels S.A. (ES) | 2000-03-22 | — | — | EP | claimed |
| EP-0767162-B1 | Sodium orthohydroxylate-phenol-water complexes, process for preparing same and application for isolation of sodium orthohydroxymandelate | CLARIANT FRANCE SA (FR) | 1999-12-08 | — | — | EP | claimed |
| EP-0767162-A1 | Sodium orthohydroxylate-phenol-water complexes, process for preparing same and application for isolation of sodium orthohydroxymandelate | SOCIETE FRANCAISE HOECHST Société anonyme dite: (FR) | 1997-04-09 | — | — | EP | claimed |
| EP-0536960-B1 | Preparation of 2-hydroxymandelic acids and 2-hydroxybenzaldehydes | ZENECA LTD (GB) | 1996-09-11 | — | — | EP | claimed |
| EP-0556084-B1 | Method of preparation of orthohydroxy mandelic acid and its salts | HOECHST FRANCE (FR) | 1996-04-03 | — | — | EP | claimed |
| US-5354897-A | Reacting glyoxylic acid with phenol in the presence of a tertiary amine and catalytic quantities of a trivalent metal compound | SOCIETE FRANCAISE HOECHST (FR) | 1994-10-11 | — | — | US | claimed |
| US-5248816-A | From glycolic acid and borate | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-09-28 | — | — | US | claimed |
| EP-0536960-A2 | Preparation of 2-hydroxymandelic acids and 2-hydroxybenzaldehydes | ZENECA LIMITED (GB) | 1993-04-14 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260092029-A1 | LIGAND-ENABLED SCALABLE C-H HYDROXYLATION OF BENZOIC AND PHENYLACETIC ACIDS AT ROOM TEMPERATURE | CYP2B6, CYP2A6, CYP1A1 | LMNA 2127/4885MAPK1 654/4885GABRA1 1013/4885 |
| US-20100288004-A1 | Metal Complexes Comprising A Ligand Derived From 2-Aryl-2-Hydroxyacetic Acid And A Divalent Or Trivalent Metal Cation, And Their Use | HACL2, HAO2, HCAR2 | LMNA 4698/4885MAPK1 3599/4885GABRA1 643/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.